Evidence map›Paper›PMID 38256269›Full record

ArticleInternational journal of molecular sciences2024

Comparative Characterisation of Proliferation and Apoptosis of Colonic Epithelium after Electron Irradiation with 2 GY and 25 GY.

Grigory Demyashkin, Elza Karakaeva, Susanna Saakian, Natalia Tarusova, Amina Guseinova, Anita Vays, Konstantin Gotovtsev, Dmitrii Atiakshin, Petr Shegai, Andrey Kaprin

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Grigory DemyashkinLaboratory of Histology and Immunohistochemistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.ORCID 0000-0001-8447-2600
Elza KarakaevaDepartment of Pathomorphology, National Medical Research Centre of Radiology, Ministry of Health of Russia, 125284 Moscow, Russia.
Susanna SaakianDepartment of Pathomorphology, National Medical Research Centre of Radiology, Ministry of Health of Russia, 125284 Moscow, Russia.
Natalia TarusovaLaboratory of Histology and Immunohistochemistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.ORCID 0009-0003-7200-916X
Amina GuseinovaLaboratory of Histology and Immunohistochemistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.
Anita VaysLaboratory of Histology and Immunohistochemistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.
Konstantin GotovtsevLaboratory of Histology and Immunohistochemistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.
Dmitrii AtiakshinResearch and Educational Resource Center for Immunophenotyping, Digital Spatial Profiling and Ultrastructural Analysis Innovative Technologies, RUDN University, 117198 Moscow, Russia.ORCID 0000-0002-8347-4556
Petr ShegaiDepartment of Pathomorphology, National Medical Research Centre of Radiology, Ministry of Health of Russia, 125284 Moscow, Russia.
Andrey KaprinDepartment of Pathomorphology, National Medical Research Centre of Radiology, Ministry of Health of Russia, 125284 Moscow, Russia.
Sechenov University · RUMinistry of Health of the Russian Federation · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Development of new techniques for multimodal treatment and diagnostics of various neoplasms and the improvement of current techniques can significantly increase the life expectancy of patients with carcinomas of the colon and abdominal-cavity organs, since prevention of various side effects of radiation therapy is one of the main problems of oncological care. Electron irradiation is one of the most promising types of radiation therapy. There are no data on proliferation and apoptosis of the colon epithelium after irradiation with electrons, especially in different modes (single and summary). Morphological evaluation of apoptosis and proliferation of colonic epithelium after local irradiation with electrons were conducted at doses of 2 Gy (Gray) and 25 Gy. Colon fragments from sexually mature Wistar rats (

Indexed as

ElectronsPhosphatidylinositol 3-KinasesAnimalsApoptosisCaspase 3Cell ProliferationColonEpitheliumHumansKi-67 AntigenRatsRats, WistarCaspase 3Ki-67 AntigenPhosphatidylinositol 3-Kinasescaspase-3colonelectronsirradiationKi-67radiotherapy

Identifiers

PMID38256269
PMCPMC10817034
OpenAlexW4390972104

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.