Evidence map›Paper›PMID 38256253›Full record

ArticleInternational journal of molecular sciences2024

Microbiota-Derived Extracellular Vesicles as a Postbiotic Strategy to Alleviate Diarrhea and Enhance Immunity in Rotavirus-Infected Neonatal Rats.

Sergio Martínez-Ruiz, Yenifer Olivo-Martínez, Cecilia Cordero, María J Rodríguez-Lagunas, Francisco J Pérez-Cano, Josefa Badia, Laura Baldoma

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sergio Martínez-RuizDepartament de Bioquímica i Fisiologia, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, 08028 Barcelona, Spain.ORCID 0000-0001-7394-3438
Yenifer Olivo-MartínezDepartament de Bioquímica i Fisiologia, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, 08028 Barcelona, Spain.ORCID 0000-0001-9269-3817
Cecilia CorderoDepartament de Bioquímica i Fisiologia, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, 08028 Barcelona, Spain.
María J Rodríguez-LagunasDepartament de Bioquímica i Fisiologia, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, 08028 Barcelona, Spain.ORCID 0000-0001-7870-8250
Francisco J Pérez-CanoDepartament de Bioquímica i Fisiologia, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, 08028 Barcelona, Spain.ORCID 0000-0001-6243-9164
Josefa BadiaDepartament de Bioquímica i Fisiologia, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, 08028 Barcelona, Spain.ORCID 0000-0003-0768-5033
Laura BaldomaDepartament de Bioquímica i Fisiologia, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, 08028 Barcelona, Spain.ORCID 0000-0002-7678-269X
Red de Investigación en Actividades Preventivas y Promoción de la Salud · ESInstitute of Agrifood Research and Technology · ES

Funding

Ministerio de Ciencia e Innovación PID2019-107327RB-100
6 · The paper itself

Abstract

Rotavirus (RV) infection is a major cause of acute gastroenteritis in children under 5 years old, resulting in elevated mortality rates in low-income countries. The efficacy of anti-RV vaccines is limited in underdeveloped countries, emphasizing the need for novel strategies to boost immunity and alleviate RV-induced diarrhea. This study explores the effectiveness of interventions involving extracellular vesicles (EVs) from probiotic and commensal

Indexed as

Extracellular VesiclesMicrobiotaRotavirusRotavirus InfectionsVaccinesAnimalsAnimals, NewbornChildChild, PreschoolDiarrheaEscherichia coliHumansRatsVaccinesextracellular vesiclesimmunomodulationintestinal serotoninmicrobiota–host communicationpostbioticsprobioticsrotavirus

Identifiers

PMID38256253
PMCPMC10816611
OpenAlexW4390973197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.