Evidence map›Paper›PMID 38256229›Full record

ArticleInternational journal of molecular sciences2024

Knockout of the

Darya A Savenkova, Andrey S Gudymo, Alexey N Korablev, Oleg S Taranov, Darya V Bazovkina, Nataliya V Danilchenko, Olga N Perfilyeva, Elena K Ivleva, Anastasiya A Moiseeva, Yulia A Bulanovich and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Darya A SavenkovaState Research Center of Virology and Biotechnology "Vector", Federal Service for Surveillance on Consumer Rights Protection and Human Well-Being (FBRI SRC VB "Vector", Rospotrebnadzor), Koltsovo 630559, Russia.ORCID 0009-0004-1335-6249
Andrey S GudymoState Research Center of Virology and Biotechnology "Vector", Federal Service for Surveillance on Consumer Rights Protection and Human Well-Being (FBRI SRC VB "Vector", Rospotrebnadzor), Koltsovo 630559, Russia.ORCID 0000-0001-6952-6412
Alexey N KorablevState Research Center of Virology and Biotechnology "Vector", Federal Service for Surveillance on Consumer Rights Protection and Human Well-Being (FBRI SRC VB "Vector", Rospotrebnadzor), Koltsovo 630559, Russia.
Oleg S TaranovState Research Center of Virology and Biotechnology "Vector", Federal Service for Surveillance on Consumer Rights Protection and Human Well-Being (FBRI SRC VB "Vector", Rospotrebnadzor), Koltsovo 630559, Russia.ORCID 0000-0002-6746-8092
Darya V BazovkinaFederal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Science, Lavrentieva 10, Novosibirsk 630090, Russia.ORCID 0000-0001-5786-7965
Nataliya V DanilchenkoState Research Center of Virology and Biotechnology "Vector", Federal Service for Surveillance on Consumer Rights Protection and Human Well-Being (FBRI SRC VB "Vector", Rospotrebnadzor), Koltsovo 630559, Russia.
Olga N PerfilyevaState Research Center of Virology and Biotechnology "Vector", Federal Service for Surveillance on Consumer Rights Protection and Human Well-Being (FBRI SRC VB "Vector", Rospotrebnadzor), Koltsovo 630559, Russia.
Elena K IvlevaState Research Center of Virology and Biotechnology "Vector", Federal Service for Surveillance on Consumer Rights Protection and Human Well-Being (FBRI SRC VB "Vector", Rospotrebnadzor), Koltsovo 630559, Russia.
Anastasiya A MoiseevaState Research Center of Virology and Biotechnology "Vector", Federal Service for Surveillance on Consumer Rights Protection and Human Well-Being (FBRI SRC VB "Vector", Rospotrebnadzor), Koltsovo 630559, Russia.
Yulia A BulanovichState Research Center of Virology and Biotechnology "Vector", Federal Service for Surveillance on Consumer Rights Protection and Human Well-Being (FBRI SRC VB "Vector", Rospotrebnadzor), Koltsovo 630559, Russia.
Elena V RoshchinaState Research Center of Virology and Biotechnology "Vector", Federal Service for Surveillance on Consumer Rights Protection and Human Well-Being (FBRI SRC VB "Vector", Rospotrebnadzor), Koltsovo 630559, Russia.
Irina A SerovaFederal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Science, Lavrentieva 10, Novosibirsk 630090, Russia.
Nariman R BattulinNovosibirsk State University, Pirogova 2, Novosibirsk 630090, Russia.ORCID 0000-0003-0611-0203
Elizabeth A KulikovaFederal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Science, Lavrentieva 10, Novosibirsk 630090, Russia.ORCID 0000-0001-9102-1525
Dmitry V YudkinState Research Center of Virology and Biotechnology "Vector", Federal Service for Surveillance on Consumer Rights Protection and Human Well-Being (FBRI SRC VB "Vector", Rospotrebnadzor), Koltsovo 630559, Russia.ORCID 0000-0002-8940-9173
State Research Center of Virology and Biotechnology VECTOR · RUInstitute of Cytology and Genetics · RUNovosibirsk State University · RU

Funding

State Assignment State Assignment No. 10/21 (FBRI SRC VB 'Vector' Rospotrebnadzor)
6 · The paper itself

Abstract

Tumor necrosis factor alpha (TNF-α) is a cytokine that is responsible for many processes associated with immune response and inflammation. It is involved in the development of an antiviral response to many virus infections. This factor was shown to be activated in influenza A virus infection, which enhances production of other cytokines. The overexpression of these cytokines can lead to a cytokine storm. To study the role of TNF-α in the development of pathologies associated with viral infection, we generated a

Indexed as

Influenza A virusOrthomyxoviridae InfectionsTumor Necrosis Factor-alphaAnimalsCytokinesMiceMice, KnockoutCytokinesTumor Necrosis Factor-alphaCRISPR/Cas9H1N1influenza A virusknockout miceTNF-α

Identifiers

PMID38256229
PMCPMC10816899
OpenAlexW4390985376

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.