Evidence map›Paper›PMID 38256191›Full record

ArticleInternational journal of molecular sciences2024

The Effects of DNA Methylation on Cytoplasmic Male Sterility in Sugar Beet.

Jiamin Weng, Hui Wang, Dayou Cheng, Tianjiao Liu, Deyong Zeng, Cuihong Dai, Chengfei Luo

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiamin WengSchool of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, China.
Hui WangSchool of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, China.
Dayou ChengSchool of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, China.
Tianjiao LiuSchool of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, China.
Deyong ZengSchool of Medicine and Health, Harbin Institute of Technology, Harbin 150001, China.
Cuihong DaiSchool of Medicine and Health, Harbin Institute of Technology, Harbin 150001, China.
Chengfei LuoSchool of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, China.

Funding

National Natural Science Foundation of China 31771864
6 · The paper itself

Abstract

DNA methylation is widely found in higher plants and can control gene expression by regulation without changing the DNA sequence. In this study, the whole-genome methylation map of sugar beet was constructed by WGBS (whole-genome bisulfite sequencing) technology, and the results of WGBS were verified by bisulfite transformation, indicating that the results of WGBS technology were reliable. In addition, 12 differential methylation genes (DMGs) were identified, which were related to carbohydrate and energy metabolism, pollen wall development, and endogenous hormone regulation. Quantitative real-time PCR (qRT-PCR) showed that 75% of DMG expression levels showed negative feedback with methylation level, indicating that DNA methylation can affect gene expression to a certain extent. In addition, we found hypermethylation inhibited gene expression, which laid a foundation for further study on the molecular mechanism of DNA methylation at the epigenetic level in sugar beet male sterility.

Indexed as

Beta vulgarisDNA MethylationSulfitesPlant InfertilitySugarsVegetableshydrogen sulfiteSugarsSulfitescytoplasmic male sterilityDNA methylationmethylated genesugar beetwhole-genome bisulfite sequencing

Identifiers

PMID38256191
PMCPMC10817047

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.