Evidence map›Paper›PMID 38256104›Full record

ArticleInternational journal of molecular sciences2024

Identification and Validation of a Prognostic Signature Derived from the Cancer Stem Cells for Oral Squamous Cell Carcinoma.

Mingxuan Shi, Ke Huang, Jiaqi Wei, Shiqi Wang, Weijia Yang, Huihui Wang, Yi Li

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. ATherapeutic advances in medical oncology · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mingxuan ShiKey Laboratory of Dental Maxillofacial Reconstruction and Biological Intelligence Manufacturing, School of Stomatology, Lanzhou University, Lanzhou 730030, China.ORCID 0000-0001-9161-9906
Ke HuangKey Laboratory of Dental Maxillofacial Reconstruction and Biological Intelligence Manufacturing, School of Stomatology, Lanzhou University, Lanzhou 730030, China.ORCID 0000-0002-8257-5558
Jiaqi WeiKey Laboratory of Dental Maxillofacial Reconstruction and Biological Intelligence Manufacturing, School of Stomatology, Lanzhou University, Lanzhou 730030, China.
Shiqi WangKey Laboratory of Dental Maxillofacial Reconstruction and Biological Intelligence Manufacturing, School of Stomatology, Lanzhou University, Lanzhou 730030, China.
Weijia YangKey Laboratory of Dental Maxillofacial Reconstruction and Biological Intelligence Manufacturing, School of Stomatology, Lanzhou University, Lanzhou 730030, China.
Huihui WangKey Laboratory of Dental Maxillofacial Reconstruction and Biological Intelligence Manufacturing, School of Stomatology, Lanzhou University, Lanzhou 730030, China.
Yi LiKey Laboratory of Dental Maxillofacial Reconstruction and Biological Intelligence Manufacturing, School of Stomatology, Lanzhou University, Lanzhou 730030, China.

Funding

Lanzhou University Excellent Postgraduate Innovation Program (Supported by the Fundamental Research Funds for the Central Universities) lzujbky-2022-it15Natural Science Foundation of Gansu Province, China Grant No. 20JR10RA691the Fundamental Research Funds for the Central Universities lzujbky-2023-07 and lzujbky-2023-29the Key Research and Development Program of Gansu Province (International Scientific and Technological Cooperation Category) No. 23YFWA0003the Open Subject Foundation of Key Laboratory of Dental Maxillofacial Reconstruction and Bio-logical Intelligence Manufacturing, School of Stomatology, Lanzhou University, Gansu Province No. 20JR10RA653
6 · The paper itself

Abstract

The progression and metastasis of oral squamous cell carcinoma (OSCC) are highly influenced by cancer stem cells (CSCs) due to their unique self-renewal and plasticity. In this study, data were obtained from a single-cell RNA-sequencing dataset (GSE172577) in the GEO database, and LASSO-Cox regression analysis was performed on 1344 CSCs-related genes to establish a six-gene prognostic signature (6-GPS) consisting of

Indexed as

Carcinoma, Squamous CellHead and Neck NeoplasmsMouth NeoplasmsDNA-Directed RNA PolymerasesHumansNeoplastic Stem CellsPrognosisSquamous Cell Carcinoma of Head and NeckDNA-Directed RNA PolymerasesPOLR1D protein, humanADMcancer stem cellsoral squamous cell carcinomaPOLR1Dprognosis signatureRNA-sequencing

Identifiers

PMID38256104
PMCPMC10816075

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.