Evidence map›Paper›PMID 38256076›Full record

ArticleInternational journal of molecular sciences2024

Probiotic-Induced Modulation of Microbiota Composition and Antibiotic Resistance Genes Load, an In Vitro Assessment.

Alicja Maria Nogacka, Silvia Saturio, Guadalupe Monserrat Alvarado-Jasso, Nuria Salazar, Clara G de Los Reyes Gavilán, Ceferino Martínez-Faedo, Adolfo Suarez, Ruipeng Wang, Kenji Miyazawa, Gaku Harata and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Gut microbes · 2025
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Alicja Maria NogackaDepartment of Microbiology and Biochemistry of Dairy Products, Instituto de Productos Lácteos de Asturias, Consejo Superior de Investigaciones Científicas (IPLA-CSIC), 33300 Villaviciosa, Spain.ORCID 0000-0001-8300-6149
Silvia SaturioDepartment of Microbiology and Biochemistry of Dairy Products, Instituto de Productos Lácteos de Asturias, Consejo Superior de Investigaciones Científicas (IPLA-CSIC), 33300 Villaviciosa, Spain.
Guadalupe Monserrat Alvarado-JassoDepartment of Microbiology and Biochemistry of Dairy Products, Instituto de Productos Lácteos de Asturias, Consejo Superior de Investigaciones Científicas (IPLA-CSIC), 33300 Villaviciosa, Spain.
Nuria SalazarDepartment of Microbiology and Biochemistry of Dairy Products, Instituto de Productos Lácteos de Asturias, Consejo Superior de Investigaciones Científicas (IPLA-CSIC), 33300 Villaviciosa, Spain.ORCID 0000-0003-1435-7628
Clara G de Los Reyes GavilánDepartment of Microbiology and Biochemistry of Dairy Products, Instituto de Productos Lácteos de Asturias, Consejo Superior de Investigaciones Científicas (IPLA-CSIC), 33300 Villaviciosa, Spain.ORCID 0000-0001-9396-6311
Ceferino Martínez-FaedoEndocrinology and Nutrition Service, Central University Hospital of Asturias (HUCA), 33011 Oviedo, Spain.
Adolfo SuarezDiet, Microbiota and Health Group, Instituto de Investigación Sanitaria del Principado de Asturias (DIMISA-ISPA), 33011 Oviedo, Spain.
Ruipeng WangTechnical Research Laboratory, Takanashi Milk Products Co., Ltd., Yokohama 241-0021, Japan.
Kenji MiyazawaTechnical Research Laboratory, Takanashi Milk Products Co., Ltd., Yokohama 241-0021, Japan.
Gaku HarataTechnical Research Laboratory, Takanashi Milk Products Co., Ltd., Yokohama 241-0021, Japan.
Akihito EndoDepartment of Food, Aroma and Cosmetic Chemistry, Tokyo University of Agriculture, Abashiri, Hokkaido 099-2493, Japan.ORCID 0000-0002-7108-1202
Silvia ArboleyaDepartment of Microbiology and Biochemistry of Dairy Products, Instituto de Productos Lácteos de Asturias, Consejo Superior de Investigaciones Científicas (IPLA-CSIC), 33300 Villaviciosa, Spain.ORCID 0000-0002-6155-5822
Miguel GueimondeDepartment of Microbiology and Biochemistry of Dairy Products, Instituto de Productos Lácteos de Asturias, Consejo Superior de Investigaciones Científicas (IPLA-CSIC), 33300 Villaviciosa, Spain.ORCID 0000-0002-0192-901X
Consejo Superior de Investigaciones Científicas · ESMegmilk Snow Brand (Japan) · JPHospital Universitario Central de Asturias · ESTokyo University of Agriculture · JP

Funding

MCIN AGL2017-83653-RMinistry of Science, Innovation and Universities IJCI-2017-32156Principality of Asturias AYUD/2021/ 50981
6 · The paper itself

Abstract

The imbalance of the gut microbiota (GM) is known as dysbiosis and is associated with disorders such as obesity. The increasing prevalence of microorganisms harboring antibiotic resistance genes (ARG) in the GM has been reported as a potential risk for spreading multi-drug-resistant pathogens. The objective of this work was the evaluation, in a fecal culture model, of different probiotics for their ability to modulate GM composition and ARG levels on two population groups, extremely obese (OB) and normal-weight (NW) subjects. Clear differences in the basal microbiota composition were observed between NW and OB donors. The microbial profile assessed by metataxonomics revealed the broader impact of probiotics on the OB microbiota composition. Also, supplementation with probiotics promoted significant reductions in the absolute levels of

Indexed as

ActinobacteriaGastrointestinal MicrobiomeMicrobiotaProbioticsAnti-Bacterial AgentsDrug Resistance, MicrobialHumansObesityAnti-Bacterial Agentsantibiotic resistance genesextreme obesityfecal culturegut microbiotaprobiotics

Identifiers

PMID38256076
PMCPMC10816173
OpenAlexW4390882533

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.