Evidence map›Paper›PMID 38256007›Full record

ArticleInternational journal of molecular sciences2024

Comparison of Nuclear Medicine Therapeutics Targeting PSMA among Alpha-Emitting Nuclides.

Kazuko Kaneda-Nakashima, Yoshifumi Shirakami, Yuichiro Kadonaga, Tadashi Watabe, Kazuhiro Ooe, Xiaojie Yin, Hiromitsu Haba, Kenji Shirasaki, Hidetoshi Kikunaga, Kazuaki Tsukada and 4 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Evaluation ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Kazuko Kaneda-NakashimaLaboratory of Radiation Biological Chemistry, FRC, Graduate School of Science, Osaka University, Toyonaka 560-0043, Japan.ORCID 0000-0001-6657-5059
Yoshifumi ShirakamiMS-CORE, FRC, Graduate School of Science, Osaka University, Toyonaka 560-0043, Japan.ORCID 0000-0003-2352-9057
Yuichiro KadonagaMS-CORE, FRC, Graduate School of Science, Osaka University, Toyonaka 560-0043, Japan.
Tadashi WatabeMS-CORE, FRC, Graduate School of Science, Osaka University, Toyonaka 560-0043, Japan.
Kazuhiro OoeMS-CORE, FRC, Graduate School of Science, Osaka University, Toyonaka 560-0043, Japan.
Xiaojie YinNishina Center for Accelerator-Based Science Nuclear Chemistry Group, RIKEN, Wako 351-0198, Japan.
Hiromitsu HabaNishina Center for Accelerator-Based Science Nuclear Chemistry Group, RIKEN, Wako 351-0198, Japan.
Kenji ShirasakiLaboratory of Alpha-Ray Emitters, Institute for Materials Research, Tohoku University, Sendai 980-8577, Japan.ORCID 0000-0002-2841-3558
Hidetoshi KikunagaResearch Center for Electron Photon Science, Tohoku University, Sendai 982-0826, Japan.
Kazuaki TsukadaResearch Group of Heavy Element Nuclear Science, Advanced Science Research Center, Japan Atomic Energy Agency, Naka-gun 319-1195, Japan.
Atsushi ToyoshimaMS-CORE, FRC, Graduate School of Science, Osaka University, Toyonaka 560-0043, Japan.
Jens CardinaleNuclear Medicine Department, University Hospital Düsseldorf, 40225 Düsseldorf, Germany.ORCID 0000-0001-6558-966X
Frederik L GieselNuclear Medicine Department, University Hospital Düsseldorf, 40225 Düsseldorf, Germany.
Koichi FukaseMS-CORE, FRC, Graduate School of Science, Osaka University, Toyonaka 560-0043, Japan.ORCID 0000-0001-8844-0710

Funding

JAEA and the GIMRT Collaborative Research Program of the Institute for Materials Research, Tohoku University 202212-RDKGE-0046Japan Agency for Medical Research and Development JP23ym0126091
6 · The paper itself

Abstract

Currently, targeted alpha therapy (TAT) is a new therapy involving the administration of a therapeutic drug that combines a substance of α-emitting nuclides that kill cancer cells and a drug that selectively accumulates in cancer cells. It is known to be effective against cancers that are difficult to treat with existing methods, such as cancer cells that are widely spread throughout the whole body, and there are high expectations for its early clinical implementation. The nuclides for TAT, including

Indexed as

Prostate-Specific AntigenProstatic NeoplasmsRadioisotopesHalf-LifeHumansMaleNuclear MedicineProstate-Specific AntigenRadioisotopesactinium-225astatine-211cytotoxicitydouble strand brakePSMAreproductive capability

Identifiers

PMID38256007
PMCPMC10815831

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.