Evidence map›Paper›PMID 38255996›Full record

ArticleInternational journal of molecular sciences2024

Expression Pattern and Prognostic Significance of the Long Non-Coding RNA Metastasis-Associated Lung Adenocarcinoma Transcript 1 in Chronic Lymphocytic Leukemia.

Kristina Tomic Vujovic, Milena Ugrin, Natasa Tosic, Vojin Vukovic, Irena Marjanovic, Tatjana Kostic, Sanja Stankovic, Vladimir Otasevic, Sofija Sarac, Darko Antic and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Kristina Tomic VujovicClinic for Hematology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0009-0001-1573-570X
Milena UgrinInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, 11042 Belgrade, Serbia.
Natasa TosicInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, 11042 Belgrade, Serbia.ORCID 0000-0002-1293-6215
Vojin VukovicClinic for Hematology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
Irena MarjanovicInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, 11042 Belgrade, Serbia.
Tatjana KosticInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, 11042 Belgrade, Serbia.
Sanja StankovicCenter for Medical Biochemistry, University Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0003-0890-535X
Vladimir OtasevicClinic for Hematology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0002-8690-1357
Sofija SaracClinic for Hematology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
Darko AnticClinic for Hematology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0002-2608-1342
Sonja PavlovicInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, 11042 Belgrade, Serbia.
Teodora Karan-DjurasevicInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, 11042 Belgrade, Serbia.ORCID 0000-0002-6156-0584
University of Belgrade · RSUniversity of Kragujevac · RS

Funding

Ministry of Education, Science and Technological Development, Republic of Serbia 451-03-47/2023-01/200042
6 · The paper itself

Abstract

Dysregulated expression of the long non-coding RNA MALAT1 has been implicated in the pathogenesis and progression of a variety of cancers, including hematological malignancies, but it has been poorly investigated in chronic lymphocytic leukemia (CLL). In this study, the expression of MALAT1 was measured using a quantitative reverse-transcriptase polymerase chain reaction in the peripheral blood mononuclear cells of 114 unselected, newly diagnosed CLL patients in order to analyze its association with clinical, laboratory, and molecular patients' characteristics at diagnosis, as well as its prognostic relevance. MALAT1 was found to be upregulated in CLL patients in comparison to healthy controls, and expression levels were not related to age, leukocyte, lymphocyte and platelet count, serum β2-microglobulin, and

Indexed as

Hematologic NeoplasmsLeukemia, Lymphocytic, Chronic, B-CellRNA, Long NoncodingHumansLeukocytes, MononuclearPrognosisRNA, Long Noncodingchronic lymphocytic leukemiaexpressionlong non-coding RNAMALAT1prognosis

Identifiers

PMID38255996
PMCPMC10815316
OpenAlexW4390751745

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.