Evidence map›Paper›PMID 38255955›Full record

ReviewInternational journal of molecular sciences2024

Is Physical Activity an Efficient Strategy to Control the Adverse Effects of Persistent Organic Pollutants in the Context of Obesity? A Narrative Review.

Quentin A Serrano, Sébastien Le Garf, Vincent Martin, Serge S Colson, Nicolas Chevalier

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pollution, stress response, and obesity: A systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Quentin A SerranoUniversité Côte d'Azur, LAMHESS, France.
Sébastien Le GarfUniversité Côte d'Azur, CHU, INSERM, C3M, France.
Vincent MartinUniversité Clermont Auvergne, AME2P, F-63000 Clermont-Ferrand, France.ORCID 0000-0002-6681-1610
Serge S ColsonUniversité Côte d'Azur, LAMHESS, France.ORCID 0000-0002-3315-9486
Nicolas ChevalierUniversité Côte d'Azur, CHU, INSERM, C3M, France.ORCID 0000-0001-7160-4301
Inserm · FRUniversité Côte d'Azur · FRInstitut Universitaire de France · FR

Funding

Agence Nationale de la Recherche ANR-15-IDEX-01Conseil Régional Provence-Alpes-Côte d'Azur no number
6 · The paper itself

Abstract

Obesity affects nearly 660 million adults worldwide and is known for its many comorbidities. Although the phenomenon of obesity is not fully understood, science regularly reveals new determinants of this pathology. Among them, persistent organic pollutants (POPs) have been recently highlighted. Mainly lipophilic, POPs are normally stored in adipose tissue and can lead to adverse metabolic effects when released into the bloodstream. The main objective of this narrative review is to discuss the different pathways by which physical activity may counteract POPs' adverse effects. The research that we carried out seems to indicate that physical activity could positively influence several pathways negatively influenced by POPs, such as insulin resistance, inflammation, lipid accumulation, adipogenesis, and gut microbiota dysbiosis, that are associated with the development of obesity. This review also indicates how, through the controlled mobilization of POPs, physical activity could be a valuable approach to reduce the concentration of POPs in the bloodstream. These findings suggest that physical activity should be used to counteract the adverse effects of POPs. However, future studies should accurately assess its impact in specific situations such as bariatric surgery, where weight loss promotes POPs' blood release.

Indexed as

Drug-Related Side Effects and Adverse ReactionsEnvironmental PollutantsAdultExerciseHumansObesityPersistent Organic PollutantsEnvironmental PollutantsPersistent Organic Pollutantsadipogenesisadipose tissuebariatric surgeryendocrine disruptorsinflammationinsulin resistancelipidmicrobiota

Identifiers

PMID38255955
PMCPMC10815489
OpenAlexW4390704376

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.