Evidence map›Paper›PMID 38255938›Full record

ArticleInternational journal of molecular sciences2024

Embers of the Past: Early Childhood Traumas Interact with Variation in

Zsuliet Kristof, Zsofia Gal, Dora Torok, Nora Eszlari, Sara Sutori, Beata Sperlagh, Ian M Anderson, Bill Deakin, Gyorgy Bagdy, Gabriella Juhasz and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.6field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Frontiers in psychiatry · 2026
    Article
  3. Review
  4. P2X7 Variants in Pathophysiology.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Zsuliet KristofDepartment of Psychiatry and Psychotherapy, Semmelweis University, Balassa utca 6, 1082 Budapest, Hungary.ORCID 0000-0001-5041-0444
Zsofia GalDepartment of Pharmacodynamics, Faculty of Pharmacy, Semmelweis University, Nagyvarad ter 4, 1089 Budapest, Hungary.ORCID 0000-0002-9441-1497
Dora TorokDepartment of Pharmacodynamics, Faculty of Pharmacy, Semmelweis University, Nagyvarad ter 4, 1089 Budapest, Hungary.
Nora EszlariDepartment of Pharmacodynamics, Faculty of Pharmacy, Semmelweis University, Nagyvarad ter 4, 1089 Budapest, Hungary.ORCID 0000-0003-4913-028X
Sara SutoriNational Centre for Suicide Research and Prevention (NASP), Department of Learning, Informatics, Management and Ethics, Karolinska Institutet, Granits väg 4, 17165 Solna, Sweden.ORCID 0000-0003-3468-0780
Beata SperlaghLaboratory of Molecular Pharmacology, HUN-REN Institute of Experimental Medicine, Szigony utca 43, 1083 Budapest, Hungary.
Ian M AndersonDivision of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biological, Medical and Human Sciences, The University of Manchester and Manchester Academic Health Sciences Centre, 46 Grafton Street, Manchester M13 9NT, UK.
Bill DeakinDivision of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biological, Medical and Human Sciences, The University of Manchester and Manchester Academic Health Sciences Centre, 46 Grafton Street, Manchester M13 9NT, UK.ORCID 0000-0002-2750-962X
Gyorgy BagdyDepartment of Pharmacodynamics, Faculty of Pharmacy, Semmelweis University, Nagyvarad ter 4, 1089 Budapest, Hungary.
Gabriella JuhaszDepartment of Pharmacodynamics, Faculty of Pharmacy, Semmelweis University, Nagyvarad ter 4, 1089 Budapest, Hungary.
Xenia GondaDepartment of Psychiatry and Psychotherapy, Semmelweis University, Balassa utca 6, 1082 Budapest, Hungary.ORCID 0000-0001-9015-4203
Semmelweis University · HUManchester Academic Health Science Centre · GBHUN-REN Institute of Experimental Medicine · HUKarolinska Institutet · SE

Funding

ERA PerMed ERAPERMED2019-108Hungarian Academy of Sciences MTA-SE Neuropsychopharmacology and Neurochemistry Research GroupHungarian Brain Research Program 2017-1.2.1-NKP-2017-00002Hungarian Brain Research Program 3.0 NAP2022-I-4/2022Hungarian National Research, Development, and Innovation Office K 143391Hungarian Research and Development Fund 131629Ministry of Innovation and Technology of Hungary from the National Research, Development and Innovation Fund, financed under the TKP2021-EGA funding scheme TKP2021-EGA-25National Research, Development and Innovation Office, Hungary 2019-2.1.7-ERA-NET-2020-00005Sixth Framework Program of the European Union, NewMood LSHM-CT-2004-503474
6 · The paper itself

Abstract

Both early childhood traumatic experiences and current stress increase the risk of suicidal behaviour, in which immune activation might play a role. Previous research suggests an association between mood disorders and

Indexed as

Adverse Childhood ExperiencesNeuroinflammatory DiseasesReceptors, Purinergic P2X7AffectChild, PreschoolGenotypeHumansSuicidal IdeationP2RX7 protein, humanReceptors, Purinergic P2X7childhood adversitiesGxE interactionneuroinflammationP2RX7recent life eventsstresssuicide

Identifiers

PMID38255938
PMCPMC10815854
OpenAlexW4390704688

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.