Evidence map›Paper›PMID 38255922›Full record

ArticleInternational journal of molecular sciences2024

Aliskiren-Loaded Nanoparticles Downregulate (Pro)renin Receptor and ACE Gene Expression in the Heart of Spontaneously Hypertensive Rats: Effect on NADPH Oxidase.

Andrej Barta, Martina Cebova, Andrej Kovac, Martina Koneracka, Vlasta Zavisova, Olga Pechanova

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Andrej BartaInstitute of Normal and Pathological Physiology, Centre of Experimental Medicine, Slovak Academy of Sciences, 813 71 Bratislava, Slovakia.
Martina CebovaInstitute of Normal and Pathological Physiology, Centre of Experimental Medicine, Slovak Academy of Sciences, 813 71 Bratislava, Slovakia.ORCID 0000-0003-0132-670X
Andrej KovacInstitute of Neuroimunology, Slovak Academy of Sciences, 813 71 Bratislava, Slovakia.ORCID 0000-0002-3223-8705
Martina KonerackaInstitute of Experimental Physics, Slovak Academy of Sciences, 040 01 Kosice, Slovakia.
Vlasta ZavisovaInstitute of Experimental Physics, Slovak Academy of Sciences, 040 01 Kosice, Slovakia.
Olga PechanovaInstitute of Normal and Pathological Physiology, Centre of Experimental Medicine, Slovak Academy of Sciences, 813 71 Bratislava, Slovakia.ORCID 0000-0001-5476-2949
Slovak Academy of Sciences · SK

Funding

European Regional Development Fund ITMS2014+: 313011AVG3, 313011W428VEGA 2/0025/23, 1/0048/23, 2/0132/20, 2/0118/21
6 · The paper itself

Abstract

We aimed to determine effects of aliskiren, a direct renin inhibitor, loaded onto polymeric nanoparticles on the (pro)renin receptor (

Indexed as

AmidesFumaratesNanoparticlesProrenin ReceptorAnimalsGene ExpressionMaleMyocytes, CardiacNADPH OxidasesPolyenesRatsRats, Inbred SHRaliskirenAmidesFumaratesNADPH OxidasesPolyenesProrenin ReceptorACEaliskirenangiotensin II type 1 receptorhearthypertensionNADPH oxidasePLA nanoparticlespro(renin) receptor

Identifiers

PMID38255922
PMCPMC10815459
OpenAlexW4390702541

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.