ReviewInternational journal of molecular sciences2024
Molecular Biology of Meniscal Healing: A Narrative Review.
Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
13 citing papers in PubMed, 17 citations in OpenAlex.
- Open Intrameniscal Examination and Reduction of Depressed Tibial Plateau Fracture.Arthroscopy techniques · 2026Article
- Osteoarthritis Progression After Medial Meniscus Posterior Root Repair: An Analysis of Surgical Timing and Baseline Degenerative Severity.Orthopaedic journal of sports medicine · 2026Article
- Rethinking meniscal repair in patients over 40: Extending the boundaries of joint preservation.World journal of methodology · 2026Review
- Histological analysis of age-related degeneration in human female and male knee cartilage and meniscus.Osteoarthritis and cartilage open · 2026Article
- Biologic Augmentation for Meniscus Repair: A Narrative Review.Bioengineering (Basel, Switzerland) · 2026Review
- Multi-functional Small Molecule for Regenerative Healing of Avascular Meniscus Tears: Modulation of Inflammation, Differentiation, and Multi-Tissue Crosstalk.Theranostics · 2026Article
- Secretome from human placenta-derived mesenchymal stem cells repairs mechanically induced meniscus injury in mice by activating the proliferation and suppressing the apoptosis of endogenous meniscus progenitor cells.Stem cell research & therapy · 2025Article
- Molecular treatments to reduce catabolic effects in human meniscus explant models.Osteoarthritis and cartilage open · 2025Article
- Global trends and research landscape of arthroscopic therapy and exercise rehabilitation in meniscal tear: a bibliometric analysis.Journal of orthopaedic surgery and research · 2025Article
- Why Hoop Tension Matters: A Biomechanical Perspective on Medial Meniscus Posterior Root Tears-A Narrative Review.Bioengineering (Basel, Switzerland) · 2025Review
- Growth differentiation factor 5 improves meniscal healing in a pilot study on rats.Journal of experimental orthopaedics · 2025Article
- Meniscal Tear Repair: What's New in the Literature?Translational sports medicine · 2025Review
- Molecular Aspects of Cartilage Microfracturation: Rehabilitation Insights.Orthopedic reviews · 2025Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review provides insights at the molecular level into the current and old methods for treating meniscal injuries. Meniscal injuries have been found to have a substantial impact on the progression of osteoarthritis. In line with the "save the meniscus" approach, meniscectomy is considered a last-resort treatment. Nevertheless, it is important to note that mechanical repair alone may not achieve the complete restoration of the meniscus. A deep understanding of the healing pathways could lead to future improvements in meniscal healing. The inclusion of cytokines and chemokines has the potential to facilitate the process of tear repair or impede the inflammatory catabolic cascade. MicroRNA (miRNA) could serve as a potential biomarker for meniscal degeneration, and RNA injections might promote collagen and growth factor production. The critical aspect of the healing process is angiogenesis within the inner zone of the meniscus. The use of collagen scaffolds and the implantation of autologous meniscus fragments have been successfully integrated into clinical settings. These findings are encouraging and underscore the need for well-designed clinical trials to explore the most effective factors that can enhance the process of meniscal repair.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.