Evidence map›Paper›PMID 38255835›Full record

ArticleInternational journal of molecular sciences2024

Differential microRNA Expression Analysis in Patients with HPV-Infected Ovarian Neoplasms.

Dariusz Jarych, Damian Mikulski, Miłosz Wilczyński, Jacek R Wilczyński, Katarzyna D Kania, Daria Haręża, Andrzej Malinowski, Ewelina Perdas, Mateusz Nowak, Edyta Paradowska

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dariusz JarychLaboratory of Virology, Institute of Medical Biology, Polish Academy of Sciences, 93-232 Lodz, Poland.ORCID 0000-0003-1303-7163
Damian MikulskiDepartment of Biostatistics and Translational Medicine, Medical University of Lodz, 92-215 Lodz, Poland.ORCID 0000-0002-2806-2583
Miłosz WilczyńskiDepartment of Surgical, Endoscopic and Oncological Gynecology, Institute of the Polish Mother's Health Center, 93-338 Lodz, Poland.ORCID 0000-0002-5720-427X
Jacek R WilczyńskiDepartment of Surgical and Oncological Gynecology, Medical University of Lodz, 90-419 Lodz, Poland.ORCID 0000-0002-2072-6533
Katarzyna D KaniaLaboratory of Virology, Institute of Medical Biology, Polish Academy of Sciences, 93-232 Lodz, Poland.ORCID 0000-0002-0673-596X
Daria HarężaLaboratory of Virology, Institute of Medical Biology, Polish Academy of Sciences, 93-232 Lodz, Poland.
Andrzej MalinowskiDepartment of Surgical, Endoscopic and Oncological Gynecology, Institute of the Polish Mother's Health Center, 93-338 Lodz, Poland.
Ewelina PerdasDepartment of Biostatistics and Translational Medicine, Medical University of Lodz, 92-215 Lodz, Poland.ORCID 0000-0002-2321-2976
Mateusz NowakDepartment of Gynecology and Obstetrics, Tomaszow Health Center, 97-200 Tomaszow Mazowiecki, Poland.ORCID 0009-0009-4404-3348
Edyta ParadowskaLaboratory of Virology, Institute of Medical Biology, Polish Academy of Sciences, 93-232 Lodz, Poland.ORCID 0000-0001-9446-0136

Funding

National Science Center 2019/33/B/NZ7/02872
6 · The paper itself

Abstract

This study aimed to identify microRNAs (miRNAs) whose expression levels are altered by high-risk human papillomavirus (HR-HPV) infection in women with epithelial ovarian neoplasms. MiRNA expression was quantified by real-time polymerase chain reaction, while HR-HPV DNA was quantified using digital-droplet PCR. Analysis of 11 miRNAs demonstrated significantly lower hsa-miR-25-5p expression in HPV-infected compared to uninfected ovarian tissues (

Indexed as

MicroRNAsOvarian NeoplasmsPapillomavirus InfectionsFemaleHuman papillomavirus 16Human papillomavirus 18HumansProspective StudiesMicroRNAsMIRN218 microRNA, humanepithelial ovarian cancerhuman papillomavirusmicroRNAoverall survival

Identifiers

PMID38255835
PMCPMC10815566

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.