Evidence map›Paper›PMID 38255787›Full record

ArticleInternational journal of molecular sciences2024

Serum Uric Acid Associates with Systemic Complement C3 Activation in Severe ANCA-Associated Renal Vasculitides.

Eva Baier, Ingmar Alexander Kluge, Samy Hakroush, Peter Korsten, Björn Tampe

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Eva BaierDepartment of Nephrology and Rheumatology, University Medical Center Göttingen, 37075 Göttingen, Germany.ORCID 0000-0001-9055-1364
Ingmar Alexander KlugeInstitute of Pathology, University Medical Center Göttingen, 37075 Göttingen, Germany.
Samy HakroushInstitute of Pathology, University Medical Center Göttingen, 37075 Göttingen, Germany.ORCID 0000-0002-2843-3567
Peter KorstenDepartment of Rheumatology and Clinical Immunology, St. Josef-Stift Sendenhorst, 48324 Sendenhorst, Germany.ORCID 0000-0001-6065-5680
Björn TampeDepartment of Nephrology and Rheumatology, University Medical Center Göttingen, 37075 Göttingen, Germany.ORCID 0000-0002-4357-9863
Universitätsmedizin Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Involvement of the complement system is key to the pathogenesis of antineutrophil cytoplasmic antibody (ANCA)-associated renal vasculitis, but immunometabolic implications, especially on serum uric acid (UA) levels, still need to be elucidated. A total of 34 patients with biopsy-proven ANCA-associated renal vasculitis between 2015 and 2020 were retrospectively enrolled. Serum UA levels were correlated with clinical and histopathological characteristics, separated for critically ill (CI,

Indexed as

Anti-Neutrophil Cytoplasmic Antibody-Associated VasculitisComplement C3Antibodies, Antineutrophil CytoplasmicHumansRetrospective StudiesUric AcidAntibodies, Antineutrophil CytoplasmicComplement C3Uric AcidANCA-associated renal vasculitisanti-neutrophil cytoplasmic antibodycomplement activationcomplement C3innate immunityserum uric acid

Identifiers

PMID38255787
PMCPMC10815696
OpenAlexW4390615923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.