ReviewLife (Basel, Switzerland)2024
An Insight into Kounis Syndrome: Bridging Clinical Knowledge with Forensic Perspectives.
Review in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Arrhythmogenic Right Ventricular Cardiomyopathy Post-Mortem Assessment: A Systematic Review.International journal of molecular sciences · 2024Pooled it
- Morphological and Genetic Aspects for Post-Mortem Diagnosis of Hypertrophic Cardiomyopathy: A Systematic Review.International journal of molecular sciences · 2024Pooled it
- Kounis Syndrome in the Modern Era: A Comprehensive Review of Allergic Acute Coronary Syndromes.Journal of clinical medicine · 2026Review
- Article
- Disproportionality and Case-Based Evidence for a Possible Association Between Fluoroquinolones and Kounis Syndrome.Pharmaceuticals (Basel, Switzerland) · 2026Article
- A Rare Cause of Life-Threatening Chest Pain: Kounis Syndrome.Journal of cardiovascular development and disease · 2026Article
- Relapsing allergic bronchopulmonary aspergillosis as a trigger for Kounis syndrome: a case report.Frontiers in cardiovascular medicine · 2026Article
- Kounis Syndrome Presenting with Atrial Fibrillation and Shark-Fin ST Elevation After Multiple Bee Stings in an African Patient: A Case Report.International medical case reports journal · 2026Article
- A harmless fang with harmful consequences: Kounis syndrome after a nonvenomous snakebite.Clinical and experimental emergency medicine · 2025Article
- Paclitaxel-related type I Kounis Syndrome in a very young patient with HER2-positive breast cancer and the role of genomics to disentangle a complex therapeutic scenario: a case report and narrative review.Breast (Edinburgh, Scotland) · 2025Review
- Fatal pediatric case of Kounis syndrome and sepsis: a case report.International journal of emergency medicine · 2025Article
- Kounis syndrome: acute myocardial injury triggered by ant bite-induced anaphylaxis.Oxford medical case reports · 2025Article
- Kounis syndrome case study: When allergies break your heart.Canadian family physician Medecin de famille canadien · 2025Article
- Kounis Syndrome in Clinical Practice: Insights from Clinical Case Series and Mechanistic Pathways.Journal of clinical medicine · 2025Review
- Time to Reconsidering the Potential Role of Leech Salivary Proteins in Medicine: Type-II Kounis Syndrome Triggered by Leech Bite.Pakistan journal of medical sciences · 2025Article
- Case Report: Anaphylactic shock and ST-elevation myocardial infarction following a bee sting: two deadly diseases in a patient with Kounis syndrome.Frontiers in cardiovascular medicine · 2025Article
- Clinical Features, Course and Prognosis of Kounis Syndrome.International journal of general medicine · 2025Article
- Epidemiological Changes in Transthyretin Cardiac Amyloidosis: Evidence from In Vivo Data and Autoptic Series.Journal of clinical medicine · 2024Review
- Fatal Outcome Due to Kounis Syndrome Following Fluorescein Retinal Angiography: A Case Report.Diagnostics (Basel, Switzerland) · 2024Article
- Resuscitation of a case of allergy, infarction, and ventricular fibrillation: Kounis syndrome type II and literature review.American journal of translational research · 2024Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Kounis syndrome (KS) is an acute coronary syndrome triggered by allergic or hypersensitivity reactions. Incidence rates vary, with studies reporting 19.4 per 100.000 among all admissions and 3.4% among allergy patients. This review explores the expanding understanding of KS, encompassing various manifestations, and focusing on both clinical data and forensic findings useful in performing a diagnosis. The pathophysiology of this syndrome involves a complex interplay between allergic reactions and the cardiovascular system. Mast cell activation, histamine release, leukotrienes, cytokines, and platelet activation can contribute to coronary events. Three types of classification systems (allergic angina, allergic myocardial infarction, allergic stent thrombosis) aid in categorizing presentations. The diagnosis of KS relies on clinical presentation, laboratory findings, and imaging. Postmortem assessment of KS is based on the integration of circumstantial data, autopsy, and histological findings. Biochemical and immunohistochemical analyses also contribute to postmortem diagnosis. In conclusion, a combined, multidisciplinary approach should be used to ease the diagnostic process, which is crucial for forensic practitioners in confirming KS occurrence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.