Evidence map›Paper›PMID 38255677›Full record

ArticleLife (Basel, Switzerland)2023

Genetic Association and Differential RNA Expression of Histone (De)Acetylation-Related Genes in Pemphigus Foliaceus-A Possible Epigenetic Effect in the Autoimmune Response.

Maiara Sulzbach Denardin, Valéria Bumiller-Bini Hoch, Amanda Salviano-Silva, Sara Cristina Lobo-Alves, Gabriel Adelman Cipolla, Danielle Malheiros, Danillo G Augusto, Michael Wittig, Andre Franke, Claudia Pföhler and 10 more

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 10 institutions in 5 countries.

Maiara Sulzbach DenardinLaboratory of Human Molecular Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.ORCID 0000-0001-9661-8734
Valéria Bumiller-Bini HochLaboratory of Human Molecular Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.ORCID 0000-0003-4000-2417
Amanda Salviano-SilvaLaboratory of Human Molecular Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.ORCID 0000-0003-2741-7028
Sara Cristina Lobo-AlvesLaboratory of Human Molecular Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.
Gabriel Adelman CipollaLaboratory of Human Molecular Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.ORCID 0000-0002-2298-8617
Danielle MalheirosLaboratory of Human Molecular Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.ORCID 0000-0002-2528-9707
Danillo G AugustoLaboratory of Human Molecular Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.ORCID 0000-0001-5665-8547
Michael WittigInstitute of Clinical Molecular Biology (IKMB), Christian-Albrechts-University of Kiel, 24105 Kiel, Germany.
Andre FrankeInstitute of Clinical Molecular Biology (IKMB), Christian-Albrechts-University of Kiel, 24105 Kiel, Germany.
Claudia PföhlerDepartment of Dermatology, Saarland University Medical Center, 66421 Homburg, Germany.ORCID 0000-0003-0384-114X
Margitta WormDivision of Allergy and Immunology, Department of Dermatology, Venerology and Allergy, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.ORCID 0000-0002-3449-1245
Nina van BeekDepartment of Dermatology, University of Lübeck, 23562 Lübeck, Germany.
Matthias GoebelerDepartment of Dermatology, Venereology and Allergology, University Hospital Würzburg, 97080 Würzburg, Germany.ORCID 0000-0001-7095-9848
Miklós SárdyDepartment of Dermatology and Allergy, University Hospital, LMU Munich, 80539 Munich, Germany.
Saleh IbrahimCollege of Medicine and Health Sciences, Khalifa University, Abu Dhabi 127788, United Arab Emirates.
Hauke BuschLübeck Institute of Experimental Dermatology (LIED), University of Lübeck, 23562 Lübeck, Germany.ORCID 0000-0003-4763-4521
Enno SchmidtDepartment of Dermatology, University of Lübeck, 23562 Lübeck, Germany.
Jennifer Elisabeth HundtLübeck Institute of Experimental Dermatology (LIED), University of Lübeck, 23562 Lübeck, Germany.
Maria Luiza Petzl-ErlerLaboratory of Human Molecular Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.ORCID 0000-0002-0345-5276
Angelica Beate Winter BoldtLaboratory of Human Molecular Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.
Universidade Federal do Paraná · BRUniversity of Lübeck · DEChristian-Albrechts-Universität zu Kiel · DECharité - Universitätsmedizin Berlin · DEKhalifa University of Science and Technology · AESaarland University · DESemmelweis University · HUUniversität Hamburg · DEUniversitätsklinikum Würzburg · DEUniversity of North Carolina at Charlotte · US

Funding

Swiss National Science Foundation CRSII5_202301/1
6 · The paper itself

Abstract

Pemphigus foliaceus (PF) is an autoimmune skin blistering disease characterized by antidesmoglein-1 IgG production, with an endemic form (EPF) in Brazil. Genetic and epigenetic factors have been associated with EPF, but its etiology is still not fully understood. To evaluate the genetic association of histone (de)acetylation-related genes with EPF susceptibility, we evaluated 785 polymorphisms from 144 genes, for 227 EPF patients and 194 controls. Carriers of

Indexed as

fogo selvagemgenetic polymorphismspemphigus foliaceuspost-translational histone modificationsRNA expression

Identifiers

PMID38255677
PMCPMC10821360
OpenAlexW4390405456

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.