Evidence map›Paper›PMID 38255674›Full record

ArticleLife (Basel, Switzerland)2023

A Continuous Extraction Protocol for the Characterisation of a Sustainably Produced Natural Indigo Pigment.

Elia Frignani, Veronica D'Eusanio, Mauro Grandi, Laura Pigani, Fabrizio Roncaglia

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Study of Woad (Molecules (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elia FrignaniDepartment of Chemical and Geological Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Veronica D'EusanioDepartment of Chemical and Geological Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0002-7808-1256
Mauro GrandiG2B S.r.l., via Guareschi 25-27, 46010 Curtatone, Italy.ORCID 0009-0009-5489-8999
Laura PiganiDepartment of Chemical and Geological Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0003-2658-2371
Fabrizio RoncagliaDepartment of Chemical and Geological Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0001-7630-4375

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The sustainable industrial production of indigo necessitates a unique extraction process to separate the plant-derived compounds. Calcium compounds are added to encourage hydrolysis of these precursors and to facilitate the isolation of the final form, resulting in an organic-inorganic composite pigment with unspecified characteristics. In this study, we devised a continuous solvent extraction procedure to fractionate the organic indigoid phase within the composite pigment. Overcoming challenges posed by limited solubility in the common organic solvents, this method allows for the analysis of individual fractions, significantly enhancing resolution. Comprehensive characterisation using spectroscopic analysis, thermogravimetry, and UHPLC-MS/MS revealed the potential for quantifying primary components of the natural pigment and distinct differentiation from the synthetic dye. This approach also holds promise for establishing robust manufacturing practices in the industrial production of natural indigo.

Indexed as

bio-based pigmentcharacterisationindigosolvent extraction

Identifiers

PMID38255674
PMCPMC10817639

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.