Evidence map›Paper›PMID 38255545›Full record

ArticleMaterials (Basel, Switzerland)2024

Ecofriendly Preparation of Rosmarinic Acid-poly(vinyl alcohol) Biofilms Using NADES/DES, Ultrasounds and Optimization via a Mixture-Process Design Strategy.

Beatrice Campanella, Mattia Simoncini, Elisa Passaglia, Francesca Cicogna, Gianluca Ciancaleoni, José González-Rivera, Luca Bernazzani, Emilia Bramanti

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Beatrice CampanellaNational Research Council, Institute for the Chemistry of Organometallic Compounds, Via Giuseppe Moruzzi 1, 56124 Pisa, Italy.
Mattia SimonciniNational Research Council, Institute for the Chemistry of Organometallic Compounds, Via Giuseppe Moruzzi 1, 56124 Pisa, Italy.
Elisa PassagliaNational Research Council, Institute for the Chemistry of Organometallic Compounds, Via Giuseppe Moruzzi 1, 56124 Pisa, Italy.ORCID 0000-0001-5006-2531
Francesca CicognaNational Research Council, Institute for the Chemistry of Organometallic Compounds, Via Giuseppe Moruzzi 1, 56124 Pisa, Italy.ORCID 0000-0003-4432-0826
Gianluca CiancaleoniDepartment of Chemistry and Industrial Chemistry, University of Pisa, Via Giuseppe Moruzzi 13, 56124 Pisa, Italy.ORCID 0000-0001-5113-2351
José González-RiveraDepartment of Chemistry and Industrial Chemistry, University of Pisa, Via Giuseppe Moruzzi 13, 56124 Pisa, Italy.ORCID 0000-0002-8826-6625
Luca BernazzaniDepartment of Chemistry and Industrial Chemistry, University of Pisa, Via Giuseppe Moruzzi 13, 56124 Pisa, Italy.ORCID 0000-0001-5396-3458
Emilia BramantiNational Research Council, Institute for the Chemistry of Organometallic Compounds, Via Giuseppe Moruzzi 1, 56124 Pisa, Italy.ORCID 0000-0001-8478-7370
Institute for the Chemistry of OrganoMetallic Compounds · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Green chemistry emphasizes the isolation of biologically active compounds from plants and biomass to produce renewable, bio-based products and materials through sustainability and circularity-driven innovation processes. In this work, we have investigated the extraction of rosmarinic acid (RA), a phenolic acid with several biological properties, from aromatic herbs using ultrasounds and low environmental risk natural deep eutectic solvents (NADES). Various solvent mixtures have been investigated, and the parameters influencing the process have been studied by a mixture-process experimental design to identify the optimal RA extraction conditions. The extraction yield has been calculated by HPLC-diode array analysis. The lactic acid:ethylene glycol mixture using an ultrasound-assisted process has been found to be the most versatile solvent system, giving RA yields 127-160% higher than hydroalcoholic extraction (70% ethanol). The deep eutectic solvent nature of lactic acid:ethylene glycol has been demonstrated for the first time by multi-technique characterization (

Indexed as

bioactive materialsNADESrosmarinic acid

Identifiers

PMID38255545
PMCPMC10820272
OpenAlexW4390817418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.