ReviewMaterials (Basel, Switzerland)2024
Challenges for Field-Effect-Transistor-Based Graphene Biosensors.
Review in Materials (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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Who cites it
14 citing papers in PubMed, 47 citations in OpenAlex.
- From Sensing Mechanisms to System Co-Design: Graphene-Based Sensors and Readout Circuits.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Engineering two-dimensional electronic biosensors.Nature reviews electrical engineering · 2026Article
- Practical Applications of 2D Material FET Biosensors: Functionalization Strategies and Detection Performance.Biosensors · 2026Review
- Recent Advances in Graphene-Based Field-Effect Transistor Biosensors for Disease Biomarker Detection and Clinical Prospects.Biosensors · 2026Review
- Cross-Platform Biosensing of Immune Receptors Using Peptide-Functionalized Graphene.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Materials challenges in solid-state sensors for continuous monitoring of ions in water.Beilstein journal of nanotechnology · 2026Review
- Biosensor technologies in cancer: tools for early detection and prognostic monitoring.Biomarker research · 2025Review
- Interaction of Organic Semiconductors and Graphene Materials in the Source-Drain Channel of Field-Effect Transistors.Biosensors · 2025Article
- Graphene-Based Biosensors: Enabling the Next Generation of Diagnostic Technologies-A Review.Biosensors · 2025Review
- Recent Advances in Xenes Based FET for Biosensing Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Advanced Materials for Biological Field-Effect Transistors (Bio-FETs) in Precision Healthcare and Biosensing.Advanced healthcare materials · 2025Review
- 2D Materials in Advanced Electronic Biosensors for Point-of-Care Devices.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- Biomedical applications of graphene-based nanomaterials: recent progress, challenges, and prospects in highly sensitive biosensors.Discover nano · 2024Review
- Low-Cost Source Measure Unit (SMU) to Characterize Sensors Built on Graphene-Channel Field-Effect Transistors.Sensors (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Owing to its outstanding physical properties, graphene has attracted attention as a promising biosensor material. Field-effect-transistor (FET)-based biosensors are particularly promising because of their high sensitivity that is achieved through the high carrier mobility of graphene. However, graphene-FET biosensors have not yet reached widespread practical applications owing to several problems. In this review, the authors focus on graphene-FET biosensors and discuss their advantages, the challenges to their development, and the solutions to the challenges. The problem of Debye screening, in which the surface charges of the detection target are shielded and undetectable, can be solved by using small-molecule receptors and their deformations and by using enzyme reaction products. To address the complexity of sample components and the detection mechanisms of graphene-FET biosensors, the authors outline measures against nonspecific adsorption and the remaining problems related to the detection mechanism itself. The authors also introduce a solution with which the molecular species that can reach the sensor surfaces are limited. Finally, the authors present multifaceted approaches to the sensor surfaces that provide much information to corroborate the results of electrical measurements. The measures and solutions introduced bring us closer to the practical realization of stable biosensors utilizing the superior characteristics of graphene.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.