Evidence map›Paper›PMID 38255325›Full record

ArticleBiomedicines2024

Cell-Free Tumor DNA Detection-Based Liquid Biopsy of Plasma and Bile in Patients with Various Pancreatic Neoplasms.

Mark Jain, David Atayan, Tagir Rakhmatullin, Tatyana Dakhtler, Pavel Popov, Pavel Kim, Mikhail Viborniy, Iuliia Gontareva, Larisa Samokhodskaya, Vyacheslav Egorov

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06967662 (Pilot Study of the Effectiveness of Selective Plasma Adsorption of Extracellular DNA as a Method for Preventing Intraoperative Metastasis in Pancreatic Cancer), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06967662 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Pilot Study of the Effectiveness of Selective Plasma Adsorption of Extracellular DNA as a Method for Preventing Intraoperative Metastasis in Pancreatic Cancer

TypeinterventionalSponsorIlyinskaya Hospital, JSCRan2025 to 2027Enrolled28ConditionsPancreatic Ductal Adenocarcinoma (PDAC)ArmsSelective plasma adsorption of extracellular DNA
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Cancer genomics & proteomics
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Mark JainMedical Research and Educational Center, Lomonosov Moscow State University, 119992 Moscow, Russia.ORCID 0000-0002-6594-8113
David AtayanJoint Stock Company "Ilyinsky Hospital", 143421 Moscow, Russia.
Tagir RakhmatullinDepartment of Fundamental Medicine, Lomonosov Moscow State University, 119991 Moscow, Russia.
Tatyana DakhtlerJoint Stock Company "Ilyinsky Hospital", 143421 Moscow, Russia.
Pavel PopovJoint Stock Company "Ilyinsky Hospital", 143421 Moscow, Russia.
Pavel KimJoint Stock Company "Ilyinsky Hospital", 143421 Moscow, Russia.
Mikhail ViborniyJoint Stock Company "Ilyinsky Hospital", 143421 Moscow, Russia.ORCID 0000-0001-6551-8810
Iuliia GontarevaJoint Stock Company "Ilyinsky Hospital", 143421 Moscow, Russia.
Larisa SamokhodskayaMedical Research and Educational Center, Lomonosov Moscow State University, 119992 Moscow, Russia.
Vyacheslav EgorovJoint Stock Company "Ilyinsky Hospital", 143421 Moscow, Russia.
Russian Venture Company · RULomonosov Moscow State University · RU

Funding

Lomonosov Moscow State University 0908This research was carried out within the state assignment of Lomonosov Moscow State University 0908
6 · The paper itself

Abstract

The key challenge of cell-free tumor DNA (cftDNA) analysis in pancreatic ductal adenocarcinoma (PDAC) is overcoming its low detection rate, which is mainly explained by the overall scarcity of this biomarker in plasma. Obstructive jaundice is a frequent event in PDAC, which enables bile collection as a part of routine treatment. The aim of this study was to evaluate the performance of

Indexed as

biledigital droplet polymerase chain reactionintraductal papillary mucinous neoplasmKRAS mutationsliquid biopsypancreatic cancerpancreatic ductal adenocarcinomaplasmaprognosissurvival

Identifiers

PMID38255325
PMCPMC10813046
OpenAlexW4390971759

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.