Evidence map›Paper›PMID 38255318›Full record

ArticleBiomedicines2024

Selenium-Containing (Hetero)Aryl Hybrids as Potential Antileishmanial Drug Candidates: In Vitro Screening against

Maria Helena Fermiano, Amarith Rodrigues das Neves, Fernanda da Silva, Manuella Salustiano Andrade Barros, Camila Barbosa Vieira, André L Stein, Tiago Elias Allievi Frizon, Antonio Luiz Braga, Carla Cardozo Pinto de Arruda, Eduardo Benedetti Parisotto and 3 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Selenium biofortification: integrating one health and sustainability.Journal of the science of food and agriculture · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Maria Helena FermianoFaculdade de Ciências Farmacêuticas, Alimentos e Nutrição (FACFAN), Universidade Federal do Mato Grosso do Sul (UFMS), Campo Grande 79070-900, MS, Brazil.ORCID 0000-0002-2048-2524
Amarith Rodrigues das NevesFaculdade de Ciências Farmacêuticas, Alimentos e Nutrição (FACFAN), Universidade Federal do Mato Grosso do Sul (UFMS), Campo Grande 79070-900, MS, Brazil.
Fernanda da SilvaInstituto de Biociências (INBIO), Universidade Federal do Mato Grosso do Sul (UFMS), Campo Grande 79070-900, MS, Brazil.
Manuella Salustiano Andrade BarrosInstituto de Química (INQUI), Universidade Federal do Mato Grosso do Sul (UFMS), Campo Grande 79074-460, MS, Brazil.
Camila Barbosa VieiraLABSO, Instituto de Química (IQ), Universidade Federal de Goiás (UFG), Goiânia 74690-900, GO, Brazil.
André L SteinDepartamento de Química, Universidade Federal de Mato Grosso (UFMT), Cuiabá 78060-900, MT, Brazil.
Tiago Elias Allievi FrizonDepartamento de Energia e Sustentabilidade, Universidade Federal de Santa Catarina (UFSC), Campus Araranguá, Araranguá 88905-120, SC, Brazil.
Antonio Luiz BragaDepartamento de Química, Universidade Federal de Santa Catarina (UFSC), Florianópolis 88040-970, SC, Brazil.ORCID 0000-0001-9903-6764
Carla Cardozo Pinto de ArrudaInstituto de Biociências (INBIO), Universidade Federal do Mato Grosso do Sul (UFMS), Campo Grande 79070-900, MS, Brazil.ORCID 0000-0002-3106-781X
Eduardo Benedetti ParisottoFaculdade de Ciências Farmacêuticas, Alimentos e Nutrição (FACFAN), Universidade Federal do Mato Grosso do Sul (UFMS), Campo Grande 79070-900, MS, Brazil.ORCID 0000-0001-5934-0323
Sumbal SabaLABSO, Instituto de Química (IQ), Universidade Federal de Goiás (UFG), Goiânia 74690-900, GO, Brazil.ORCID 0000-0002-6134-7249
Jamal RafiqueInstituto de Química (INQUI), Universidade Federal do Mato Grosso do Sul (UFMS), Campo Grande 79074-460, MS, Brazil.ORCID 0000-0002-2336-040X
Thalita Bachelli RiulFaculdade de Ciências Farmacêuticas, Alimentos e Nutrição (FACFAN), Universidade Federal do Mato Grosso do Sul (UFMS), Campo Grande 79070-900, MS, Brazil.ORCID 0000-0002-4298-6475
Universidade Federal de Mato Grosso do Sul · BRUniversidade Federal de Goiás · BRUniversidade Federal de Santa Catarina · BRUniversidade Federal de Mato Grosso · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 001Instituto Nacional de Ciência e Tecnologia de Catálise em Sistemas Moleculares e Nanoestruturados INCT-Catálise/CNPq/FAPESCNational Council for Scientific and Technological Development 309975/2022-0National Council for Scientific and Technological Development 315399/2020-1National Council for Scientific and Technological Development 403210/2021-6National Council for Scientific and Technological Development 422645/2021-4
6 · The paper itself

Abstract

Leishmaniasis remains a significant global health concern, with current treatments relying on outdated drugs associated with high toxicity, lengthy administration, elevated costs, and drug resistance. Consequently, the urgent need for safer and more effective therapeutic options in leishmaniasis treatment persists. Previous research has highlighted selenium compounds as promising candidates for innovative leishmaniasis therapy. In light of this, a library of 10 selenium-containing diverse compounds was designed and evaluated in this study. These compounds included selenium-substituted indole, coumarin, chromone, oxadiazole, imidazo[1,2-

Indexed as

1,3,4-oxadiazole2,5-dihydrooxazolechromonecoumarinimidazo[1,2-a]pyridineimidazo[2,1-b]thiazoleindoleleishmaniasisorganoselenideβ-naphthol

Identifiers

PMID38255318
PMCPMC10812941
OpenAlexW4391012124

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.