Evidence map›Paper›PMID 38255174›Full record

ReviewBiomedicines2023

Hemoadsorption Therapy for Critically Ill Patients with Acute Liver Dysfunction: A Meta-Analysis and Systematic Review.

Caner Turan, Csenge Erzsébet Szigetváry, Tamás Kói, Marie Anne Engh, Işıl Atakan, László Zubek, Tamás Terebessy, Péter Hegyi, Zsolt Molnár

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Potential Clinical Use of CytoSorbLife (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Caner TuranDepartment of Anesthesiology and Intensive Therapy, Semmelweis University, 1085 Budapest, Hungary.ORCID 0000-0002-8200-7569
Csenge Erzsébet SzigetváryDepartment of Anesthesiology and Intensive Therapy, Semmelweis University, 1085 Budapest, Hungary.ORCID 0000-0003-0832-1661
Tamás KóiCentre for Translational Medicine, Semmelweis University, 1085 Budapest, Hungary.
Marie Anne EnghCentre for Translational Medicine, Semmelweis University, 1085 Budapest, Hungary.ORCID 0000-0003-4269-5130
Işıl AtakanCentre for Translational Medicine, Semmelweis University, 1085 Budapest, Hungary.
László ZubekCentre for Translational Medicine, Semmelweis University, 1085 Budapest, Hungary.
Tamás TerebessyCentre for Translational Medicine, Semmelweis University, 1085 Budapest, Hungary.
Péter HegyiCentre for Translational Medicine, Semmelweis University, 1085 Budapest, Hungary.
Zsolt MolnárDepartment of Anesthesiology and Intensive Therapy, Semmelweis University, 1085 Budapest, Hungary.ORCID 0000-0002-1468-4058
Semmelweis University · HU

Funding

Hungarian National Research, Development and Innovation Office K 138816
6 · The paper itself

Abstract

Critically ill patients are at risk of developing acute liver dysfunction as part of multiorgan failure sequelae. Clearing the blood from toxic liver-related metabolites and cytokines could prevent further organ damage. Despite the increasing use of hemoadsorption for this purpose, evidence of its efficacy is lacking. Therefore, we conducted this systematic review and meta-analysis to assess the evidence on clinical outcomes following hemoadsorption therapy. A systematic search conducted in six electronic databases (PROSPERO registration: CRD42022286213) yielded 30 eligible publications between 2011 and 2023, reporting the use of hemoadsorption for a total of 335 patients presenting with liver dysfunction related to acute critical illness. Of those, 26 are case presentations (

Indexed as

critical caredatabase meta-analysishemoadsorptionliver dysfunction

Identifiers

PMID38255174
PMCPMC10813081
OpenAlexW4390266279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.