Evidence map›Paper›PMID 38254934›Full record

ReviewGenes2023

Association between Pancreatoblastoma and Familial Adenomatous Polyposis: Review of the Literature with an Additional Case.

Andrea Remo, Silvia Negro, Riccardo Quoc Bao, Edoardo d'Angelo, Rita Alaggio, Gino Crivellari, Isabella Mammi, Rossana Intini, Francesca Bergamo, Matteo Fassan and 4 more

Open access · goldAbstract readReviewCase Reports
In one paragraph

Review in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Andrea RemoPathology Unit, ULSS9 "Scaligera", 37122 Verona, Italy.ORCID 0000-0002-2564-2988
Silvia NegroGeneral Surgery 3, Department of Surgical, Oncological and Gastroenterological Sciences, University of Padova, 35121 Padua, Italy.
Riccardo Quoc BaoGeneral Surgery 3, Department of Surgical, Oncological and Gastroenterological Sciences, University of Padova, 35121 Padua, Italy.
Edoardo d'AngeloGeneral Surgery 3, Department of Surgical, Oncological and Gastroenterological Sciences, University of Padova, 35121 Padua, Italy.
Rita AlaggioPathology Department, Ospedale Pediatrico Bambino Gesù, IRCCS, 00165 Roma, Italy.
Gino CrivellariFamilial Cancer Clinic and Oncoendocrinology, Veneto Institute of Oncology, IOV-IRCCS, 35121 Padua, Italy.
Isabella MammiFamilial Cancer Clinic and Oncoendocrinology, Veneto Institute of Oncology, IOV-IRCCS, 35121 Padua, Italy.
Rossana IntiniOncology 1, Veneto Institute of Oncology, IOV-IRCCS, 35121 Padua, Italy.
Francesca BergamoOncology 1, Veneto Institute of Oncology, IOV-IRCCS, 35121 Padua, Italy.
Matteo FassanDepartment of Medicine-DIMED, University of Padova, 35121 Padua, Italy.ORCID 0000-0001-6515-5482
Marco AgostiniGeneral Surgery 3, Department of Surgical, Oncological and Gastroenterological Sciences, University of Padova, 35121 Padua, Italy.ORCID 0000-0001-7578-1233
Marco VitellaroUnit of Hereditary Digestive Tract Tumors, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.ORCID 0000-0001-8134-5315
Salvatore PucciarelliGeneral Surgery 3, Department of Surgical, Oncological and Gastroenterological Sciences, University of Padova, 35121 Padua, Italy.ORCID 0000-0001-5289-9925
Emanuele Damiano Luca UrsoGeneral Surgery 3, Department of Surgical, Oncological and Gastroenterological Sciences, University of Padova, 35121 Padua, Italy.ORCID 0000-0002-2789-2470
University of Padua · ITIstituto Oncologico Veneto · ITBambino Gesù Children's Hospital · ITFondazione IRCCS Istituto Nazionale dei Tumori · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdult pancreatoblastoma (PBL) is a rare pancreatic malignancy, with recent evidence suggesting a possible link to familial adenomatous polyposis (FAP). This study aims to review the latest evidence and explore a possible association between adult PBL and FAP.

methodsTwo independent literature reviews were conducted: (1) on PBL and FAP, and (2) on PBL in the adult population not diagnosed with FAP.

resultsOut of 26 articles on PBL and FAP screened, 5 were selected for systematic review, including 1 additional case. We identified eight FAP-related PBL cases, with a median age of 40 (IQR: 34-50). Of these, seven (87%) occurred in adults. We found 65 cases of adult PBL not FAP-related; thus, 7 out of 65 cases (10.7%) of adult PBL reported in the literature are associated with a clinical diagnosis of FAP or were carriers of

conclusionData suggest a non-random association between adult PBL and FAP. Further research is essential to optimise surveillance protocols and develop more effective treatment strategies.

Indexed as

Adenomatous Polyposis ColiPancreatic NeoplasmsAdultGerm-Line MutationHumansfamilial adenomatous polyposisinherited tumours syndromespancreatoblastoma

Identifiers

PMID38254934
PMCPMC10815143
OpenAlexW4390275013

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.