ArticleCancers2024
Incidence and Risk Assessment of Capsular Contracture in Breast Cancer Patients following Post-Mastectomy Radiotherapy and Implant-Based Reconstruction.
Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 20 citations in OpenAlex.
- Extreme Oncoplasty: Avoiding Mastectomy and Expanding the Limits of Breast Conservation-A Comparative Study of 718 Patients.Annals of surgical oncology · 2026Article
- A Bibliometric Review of Capsular Contracture in Breast Implant: Global Trends and Research Hotspots.Plastic surgery (Oakville, Ont.) · 2026Article
- Clinical Performance of GalaFLEX® (Poly-4-Hydroxybutyrate) Scaffold Application in Aesthetic and Reconstructive Breast Surgery: A Retrospective Study.Aesthetic plastic surgery · 2026Article
- Hypofractionated Versus Conventional Postmastectomy Radiotherapy in Implant-Based Breast Reconstruction: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2026Review
- Does Patient History Influence Capsular Contracture? An Exploratory Analysis with Machine Learning.Aesthetic plastic surgery · 2026Article
- Implications of a New Generation of Tissue Expanders for Post-Mastectomy Radiotherapy in Breast Reconstruction: A Retrospective Single-Center Study.Journal of clinical medicine · 2026Article
- Shear-Wave Elastography as an Objective Diagnostic Tool for Capsular Contracture After Breast Implant Surgery: A Comparative Study.Diagnostics (Basel, Switzerland) · 2026Article
- Autologous Versus Implant-Based Breast Reconstruction: Insights From Recent Oncologic and Plastic Surgery Guidelines.Cureus · 2026Review
- Understanding Capsular Contracture: Mechanisms, Management, and Patient Outcomes in Implant-based Breast Augmentation and Reconstruction.Plastic and reconstructive surgery. Global open · 2026Article
- Article
- Impact of Surgical Delay on Two-Stage Breast Reconstruction During the COVID-19 Pandemic: A Retrospective Analysis.Journal of clinical medicine · 2025Article
- Implant-based reconstruction and adjuvant radiotherapy in breast cancer patients-current status and DEGRO recommendations.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025Review
- Post-mastectomy hypofractionated versus conventionally fractionated radiation therapy for patients receiving immediate breast reconstruction: Subgroup analysis of a phase III randomized trial.Clinical and translational radiation oncology · 2025Article
- Complications and patient-reported outcomes after radiotherapy in breast cancer patients undergoing implant-based breast reconstruction: a retrospective study from a large Chinese breast disease center.World journal of surgical oncology · 2024Article
- Article
- A Comparison of Capsular Contracture Rates after Immediate Implant-based Breast Reconstruction Using Biologic versus Synthetic Mesh.Plastic and reconstructive surgery. Global open · 2024Article
- Beyond Mastectomy: The Incidence of Subsequent Aesthetic Procedures after Mastectomy with and without Breast Reconstruction.Plastic and reconstructive surgery. Global open · 2024Article
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Authors and funding
17 authors at 2 institutions in 1 country.
Funding
Abstract
Our study aims to identify the risk factors and dosimetry characteristics associated with capsular contracture.
methodsWe retrospectively analyzed 118 women with breast cancer who underwent PMRT following an IBR between 2010 and 2022. Patients were treated with PMRT of 50.0-50.4 Gy in 25-28 fractions. Capsular contracture was categorized according to the Baker Classification for Reconstructed Breasts.
resultsAfter a median follow-up of 22 months, the incidence of clinically relevant capsular contracture (Baker III-IV) was 22.9%. Overall, capsular contracture (Baker I-IV) occurred in 56 patients (47.5%) after a median of 9 months after PMRT. The rate of reconstruction failure/implant loss was 25.4%. In the univariate analysis, postoperative complications (prolonged pain, prolonged wound healing, seroma and swelling) and regional nodal involvement were associated with higher rates of capsular contracture (
conclusionPostoperative complications and regional nodal involvement were associated with an increased risk of capsular contracture following breast reconstruction and PMRT, while none of the analyzed dosimetric factors were linked to a higher incidence. Additional studies are needed to identify further potential risk factors.
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Registered trials
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