Evidence map›Paper›PMID 38254737›Full record

ArticleCancers2024

Grade 2, 3 and Dedifferentiated Chondrosarcomas: A Comparative Study of Isocitrate Dehydrogenase-Mutant and Wild-Type Tumors with Implications for Prognosis and Therapy.

Karen Schoedel, Tanya Heim, Anette Duensing, Ines Lohse, Laura Presutti, Rebekah Belayneh, Sumail Bhogal, Anya Singh-Varma, Alexander Chang, Uma Chandran and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Karen SchoedelDepartment of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, USA.ORCID 0000-0001-5398-8962
Tanya HeimDepartment of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA 15232, USA.ORCID 0000-0002-5808-6770
Anette DuensingDepartment of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, USA.ORCID 0000-0002-0168-4067
Ines LohseDepartment of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA 15232, USA.
Laura PresuttiDepartment of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Rebekah BelaynehDepartment of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA 15232, USA.
Sumail BhogalDepartment of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA 15232, USA.
Anya Singh-VarmaSchool of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Alexander ChangDepartment of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA 15206, USA.
Uma ChandranDepartment of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA 15206, USA.
Daniel MarkerDepartment of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, USA.ORCID 0000-0001-6171-0688
Heather Szabo-RogersDepartment of Anatomy, Physiology and Pharmacology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E2, Canada.ORCID 0000-0002-7921-8031
Kurt WeissDepartment of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA 15232, USA.ORCID 0000-0003-3859-728X
University of Pittsburgh · USUniversity of Saskatchewan · CA

Funding

Pittsburgh Cure Sarcoma No grant number
6 · The paper itself

Abstract

backgroundGrade 2 and 3 and dedifferentiated chondrosarcomas (CS) are frequently associated with isocitrate dehydrogenase (

methodsFormalin-fixed paraffin-embedded material from 69 primary and recurrent grade 2, 3 and dedifferentiated CS was obtained. DNA sequencing for

resultsA set of 69 CS (28 females, 41 males), average age 65, distributed among femur, pelvis, humerus, and chest wall were identified from available clinical material. After further selection based on available

conclusionsGrade 2, 3 and dedifferentiated chondrosarcomas are further characterized by

Indexed as

chondrosarcomagenomicsisocitrate dehydrogenaseRNA sequencing

Identifiers

PMID38254737
PMCPMC10813891
OpenAlexW4390615335

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.