Evidence map›Paper›PMID 38254658›Full record

ArticleBiomolecules2023

Aberrant Mannosylated and Highly Fucosylated Glycoepitopes of Prostatic Acid Phosphatase as Potential Ligands for Dendritic-Cell Specific ICAM-Grabbing Nonintegrin (DC-SIGN) in Human Seminal Plasma-A Step towards Explaining Idiopathic Infertility.

Anna Kałuża, Katarzyna Trzęsicka, Damian Drzyzga, Mirosława Ferens-Sieczkowska

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Anna KałużaDepartment of Biochemistry and Immunochemistry, Division of Chemistry and Immunochemistry, Wroclaw Medical University, M. Skłodowskiej-Curie 48/50, 50-369 Wroclaw, Poland.ORCID 0000-0003-0161-3012
Katarzyna TrzęsickaINVICTA, Research and Development Center, Polna 64, 81-740 Sopot, Poland.ORCID 0009-0004-2728-0273
Damian DrzyzgaINVICTA, Research and Development Center, Polna 64, 81-740 Sopot, Poland.ORCID 0000-0002-6466-2412
Mirosława Ferens-SieczkowskaDepartment of Biochemistry and Immunochemistry, Division of Chemistry and Immunochemistry, Wroclaw Medical University, M. Skłodowskiej-Curie 48/50, 50-369 Wroclaw, Poland.ORCID 0000-0001-8578-7487
Wroclaw Medical University · PL

Funding

Wroclaw Medical University SUBK.A411.23.066
6 · The paper itself

Abstract

Semen prostatic acid phosphatase (PAP) has been proposed as an endogenous ligand for dendritic cell-specific ICAM-3-grabbing nonintegrin (DC-SIGN), which plays a critical immuno-modulating role in maintaining homeostasis in the female reproductive tracts. In the current study, we assumed that semen PAP bears a set of fucosylated and mannosylated glycans, which may mediate the efficient binding of PAP to DC-SIGN. To investigate this hypothesis, we developed ELISA assays using

Indexed as

Acid PhosphataseCell Adhesion MoleculesInfertilityLectins, C-TypeReceptors, Cell SurfaceSemenDC-Specific ICAM-3 Grabbing NonintegrinFemaleHumansLigandsMaleMannosePolysaccharidesAcid PhosphataseCell Adhesion MoleculesDC-Specific ICAM-3 Grabbing NonintegrinLectins, C-TypeLigandsMannosePolysaccharidesprostatic acid phosphataseReceptors, Cell SurfaceDC-SIGNdendritic-cell specific ICAM-grabbing nonintegrinidiopathic infertilityprostatic acid phosphataseseminal plasma

Identifiers

PMID38254658
PMCPMC10813591
OpenAlexW4390466691

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.