Evidence map›Paper›PMID 38254636›Full record

ArticleBiomolecules2023

Evaluation of the Mechanisms Involved in the Development of Bladder Toxicity following Exposure to Occupational Bladder Cancer Causative Chemicals Using DNA Adductome Analysis.

Shugo Suzuki, Min Gi, Masami Komiya, Asuka Obikane, Arpamas Vachiraarunwong, Masaki Fujioka, Anna Kakehashi, Yukari Totsuka, Hideki Wanibuchi

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Shugo SuzukiDepartment of Molecular Pathology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan.ORCID 0000-0001-8938-9670
Min GiDepartment of Molecular Pathology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan.
Masami KomiyaLaboratory of Environmental Toxicology and Carcinogenesis, School of Pharmacy, Nihon University, Chiba 274-8555, Japan.
Asuka ObikaneDivision of Cancer Pathophysiology, National Cancer Center Research Institute, Tokyo 104-0045, Japan.
Arpamas VachiraarunwongDepartment of Molecular Pathology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan.
Masaki FujiokaDepartment of Molecular Pathology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan.ORCID 0000-0003-0048-2874
Anna KakehashiDepartment of Molecular Pathology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan.ORCID 0000-0003-1149-1450
Yukari TotsukaLaboratory of Environmental Toxicology and Carcinogenesis, School of Pharmacy, Nihon University, Chiba 274-8555, Japan.
Hideki WanibuchiDepartment of Molecular Pathology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan.
Osaka Metropolitan University · JPNihon University · JPUniversity of Yamanashi Hospital · JP

Funding

JSPS Grant Number 22K10512Ministry of Health, Labor and Welfare, Japan (20316909)the Japan Agency for Medical Research and Development 20ck0106545h0001
6 · The paper itself

Abstract

Occupational exposure to aromatic amines (AAs) is an important risk factor for urinary bladder cancer. This study aimed to evaluate the toxicity of AAs and analyze the carcinogenic mechanisms in rat bladder by comprehensive analysis of DNA adducts (DNA adductome). DNA was extracted from the bladder epithelia of rats treated with AAs, including acetoacet-

Indexed as

AcetophenonesToluidinesUrinary BladderUrinary Bladder Neoplasms8-Hydroxy-2'-DeoxyguanosineAminesAnimalsDatabases, Nucleic AcidDNA AdductsRats2-toluidine8-Hydroxy-2'-DeoxyguanosineAcetophenonesacetovanilloneAminesDNA AdductsToluidinesbladderDNA adductomeo-toluidineoxidative stress

Identifiers

PMID38254636
PMCPMC10813811
OpenAlexW4390272404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.