Evidence map›Paper›PMID 38254490›Full record

ArticleFoods (Basel, Switzerland)2024

Olive Oil Waste as a Source of Functional Food Ingredients: Assessing Polyphenolic Content and Antioxidant Activity in Olive Leaves.

Carolina L Ronca, Sara S Marques, Alberto Ritieni, Rafael Giménez-Martínez, Luisa Barreiros, Marcela A Segundo

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  3. An Integrated Approach to Evaluate the Influence of DietaryAnimals : an open access journal from MDPI · 2026
    Article
  4. Review
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  8. Review
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  10. Article
  11. Review
  12. Article
  13. Potential Therapeutic Properties ofPharmaceuticals (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Carolina L RoncaLAQV, REQUIMTE, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, 4099-002 Porto, Portugal.ORCID 0009-0005-4057-2833
Sara S MarquesLAQV, REQUIMTE, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, 4099-002 Porto, Portugal.ORCID 0000-0002-4386-850X
Alberto RitieniDepartment of Pharmacy, Faculty of Pharmacy, University of Naples "Federico II", 80138 Naples, Italy.ORCID 0000-0003-0314-8839
Rafael Giménez-MartínezDepartment of Nutrition and Bromatology, School of Pharmacy, University of Granada, 18012 Granada, Spain.
Luisa BarreirosLAQV, REQUIMTE, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, 4099-002 Porto, Portugal.ORCID 0000-0003-3481-5809
Marcela A SegundoLAQV, REQUIMTE, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, 4099-002 Porto, Portugal.ORCID 0000-0003-2938-0214
Universidade do Porto · PTUniversidad de Granada · ESUniversity of Naples Federico II · IT

Funding

Fundação para a Ciência e a Tecnologia UIDB/50006/2020Fundação para a Ciência e a Tecnologia UIDP/50006/2020Ministero dell'Università e della ricerca (MIUR) and European Social Fund DOT18FFNZ8
6 · The paper itself

Abstract

Around two million tons of olive oil are produced in Europe annually, with Portugal being among the top five European olive oil-producing countries. Olive oil production results in a substantial amount of waste in the form of olive leaves. These discarded olive leaves contain valuable phenolic compounds with antioxidant, anti-inflammatory, hypoglycaemic, neuroprotective, and antiproliferative properties. Due to their richness in polyphenols with health-promoting properties, olive leaves can be considered a potential functional food ingredient. Thus, sustainable practices for reusing olive leaf waste are in demand. In this study, the polyphenolic content in olive leaves from different Portuguese locations was determined using HPLC-UV-Vis after defining the best fit-for-purpose liquid extraction strategy. The differences in the in vitro antioxidant activity in these samples were determined by several methodologies based on radical scavenging (against 2,2'-azino-bis-3-ethylbenzthiazoline-6-sulphonic acid (ABTS), 2,2-diphenyl-2-picrylhydrazyl (DPPH), and peroxyl radical (ORAC)) and on reducing properties (cupric-reducing antioxidant capacity (CUPRAC), and Folin-Ciocalteu assay (FC)), to unveil the relationship between the profile and quantity of polyphenols with antioxidant mechanisms and their capacity. At last, the stability of extracted compounds upon lyophilization and exposition to surrogate biological fluids was assessed, envisioning the future incorporation of olive leaves extracted compounds in food products.

Indexed as

antioxidant capacitybioactive compoundscircular economyfunctional food ingredientsMediterranean dietolive oil waste valorizationsustainable extraction

Identifiers

PMID38254490
PMCPMC10814828
OpenAlexW4390670267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.