Evidence map›Paper›PMID 38254451›Full record

ArticleAnimals : an open access journal from MDPI2024

Efficacy of Allogeneic and Xenogeneic Exosomes for the Treatment of Canine Atopic Dermatitis: A Pilot Study.

Sang-Won Kim, Kyung-Min Lim, Ssang-Goo Cho, Bokyeong Ryu, C-Yoon Kim, Seon Young Park, Kyungmin Jang, Jae Heon Jung, Cheolhyoung Park, Chulhee Choi and 1 more

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Sang-Won KimDepartment of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05029, Republic of Korea.ORCID 0000-0002-1260-3410
Kyung-Min LimDepartment of Stem Cell and Regenerative Biotechnology, Molecular & Cellular Reprogramming Center and Institute of Advanced Regenerative Science, Konkuk University, Seoul 05029, Republic of Korea.ORCID 0000-0001-5456-255X
Ssang-Goo ChoDepartment of Stem Cell and Regenerative Biotechnology, Molecular & Cellular Reprogramming Center and Institute of Advanced Regenerative Science, Konkuk University, Seoul 05029, Republic of Korea.ORCID 0000-0002-0968-7932
Bokyeong RyuDepartment of Veterinary Physiology, College of Veterinary Medicine, Konkuk University, Seoul 05029, Republic of Korea.
C-Yoon KimDepartment of Veterinary Physiology, College of Veterinary Medicine, Konkuk University, Seoul 05029, Republic of Korea.ORCID 0000-0003-1199-8024
Seon Young ParkILIAS Biologics Inc., Daejeon 34014, Republic of Korea.
Kyungmin JangILIAS Biologics Inc., Daejeon 34014, Republic of Korea.
Jae Heon JungILIAS Biologics Inc., Daejeon 34014, Republic of Korea.
Cheolhyoung ParkILIAS Biologics Inc., Daejeon 34014, Republic of Korea.
Chulhee ChoiILIAS Biologics Inc., Daejeon 34014, Republic of Korea.ORCID 0000-0001-5542-9136
Jung-Hyun KimDepartment of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05029, Republic of Korea.ORCID 0000-0003-0719-3266
Konkuk University · KR

Funding

Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry and Fisheries 321013-01
6 · The paper itself

Abstract

Canine atopic dermatitis (CAD) is a genetically predisposed inflammatory pruritic skin disease. The available treatments for CAD have several adverse effects and vary in efficacy, indicating the need for the development of improved treatments. In this study, we aimed to elucidate the therapeutic effects of allogeneic and xenogeneic exosomes on CAD. Six laboratory beagle dogs with CAD were randomly assigned to three treatment groups: control, canine exosome (cExos), or human exosome (hExos) groups. Dogs in the cExos and hExos groups were intravenously administered 1.5 mL of cExos (5 × 10

Indexed as

canine atopic dermatitisdogexosomeimmunomodulatory effectmesenchymal stem cellmicrobiome analysis

Identifiers

PMID38254451
PMCPMC10812568
OpenAlexW4390906414

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.