Evidence map›Paper›PMID 38254233›Full record

ArticleTrials2024

Thoracic paravertebral block for perioperative lung preservation during VATS pulmonary surgery: study protocol of a randomized clinical trial.

Jiayu Zhu, Biyu Wei, Lili Wu, He Li, Yi Zhang, Jinfeng Lu, Shaofei Su, Chunhua Xi, Wei Liu, Guyan Wang

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05922449 (Using Thoracic Paravertebral Block for Perioperative Lung Preservation During VATS Pulmonary Surgery), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05922449 nacompletednot on this map

Using Thoracic Paravertebral Block for Perioperative Lung Preservation During VATS Pulmonary Surgery: A Dual Center Randomized Controlled Trial

TypeinterventionalSponsorBeijing Tongren HospitalRan2023 to 2024Enrolled302ConditionsPostoperative Pulmonary ComplicationsArmsThoracic Paravertebral Block
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jiayu ZhuDepartment of Anaesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.
Biyu WeiDepartment of Anaesthesiology, Beijing Chest Hospital, Capital Medical University, Beijing, 101100, China.
Lili WuDepartment of Anaesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.
He LiDepartment of Anaesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.
Yi ZhangDepartment of Anaesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.
Jinfeng LuDepartment of Anaesthesiology, Beijing Renhe Hospital, Beijing, 102600, China.
Shaofei SuCentral Laboratory, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Chaoyang, Beijing, 100026, China.
Chunhua XiDepartment of Anaesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.
Wei LiuDepartment of Anaesthesiology, Beijing Chest Hospital, Capital Medical University, Beijing, 101100, China. lw1200@sina.com.
Guyan WangDepartment of Anaesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China. guyanwang2006@163.com.ORCID http://orcid.org/0000-0001-6957-6356
Beijing Tongren Hospital · CNCapital Medical University · CN

Funding

Beijing Hospitals Authority Clinical Medicine Development of Special Funding Support ZYLX202103Beijing Hospitals Authority's Ascent Plan DFL20220203
6 · The paper itself

Abstract

backgroundPostoperative pulmonary complications (PPCs) extend the length of stay of patients and increase the perioperative mortality rate after video-assisted thoracoscopic (VATS) pulmonary surgery. Thoracic paravertebral block (TPVB) provides effective analgesia after VATS surgery; however, little is known about the effect of TPVB on the incidence of PPCs. The aim of this study is to determine whether TPVB combined with GA causes fewer PPCs and provides better perioperative lung protection in patients undergoing VATS pulmonary surgery than simple general anaesthesia.

methodsA total of 302 patients undergoing VATS pulmonary surgery will be randomly divided into two groups: the paravertebral block group (PV group) and the control group (C group). Patients in the PV group will receive TPVB: 15 ml of 0.5% ropivacaine will be administered to the T4 and T7 thoracic paravertebral spaces before general anaesthesia induction. Patients in the C group will not undergo the intervention. Both groups of patients will be subjected to a protective ventilation strategy during the operation. Perioperative protective mechanical ventilation and standard fluid management will be applied in both groups. Patient-controlled intravenous analgesia is used for postoperative analgesia. The primary endpoint is a composite outcome of PPCs within 7 days after surgery. Secondary endpoints include blood gas analysis, postoperative lung ultrasound score, NRS score, QoR-15 score, hospitalization-related indicators and long-term prognosis indicators. DISCUSSION: This study will better evaluate the impact of TPVB on the incidence of PPCs and the long-term prognosis in patients undergoing VATS lobectomy/segmentectomy. The results may provide clinical evidence for optimizing perioperative lung protection strategies.

trial registrationClinicalTrials.gov NCT05922449 . Registered on June 25, 2023.

Indexed as

Nerve BlockThoracic Surgery, Video-AssistedAnalgesia, Patient-ControlledHumansLungRandomized Controlled Trials as TopicRespirationPostoperative analgesiaPostoperative pulmonary complicationsThoracic paravertebral blockVideo-assisted thoracoscopic surgery

Identifiers

PMID38254233
PMCPMC10801977
OpenAlexW4391110575

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.