Evidence map›Paper›PMID 38254171›Full record

ArticleLipids in health and disease2024

Predictive value of lipoprotein(a) for left atrial thrombus or spontaneous echo contrast in non-valvular atrial fibrillation patients with low CHA

Kamila Kamili, Tingting Zheng, Chaodi Luo, Xuan Wang, Gang Tian

Open access · goldAbstract read
In one paragraph

Article in Lipids in health and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kamila KamiliDepartment of Cardiovascular Medicine, First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Rd, Xi'an, Shaanxi, 710061, People's Republic of China.
Tingting ZhengDepartment of Cardiovascular Medicine, First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Rd, Xi'an, Shaanxi, 710061, People's Republic of China.
Chaodi LuoDepartment of Cardiovascular Medicine, First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Rd, Xi'an, Shaanxi, 710061, People's Republic of China.
Xuan WangDepartment of Cardiovascular Medicine, First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Rd, Xi'an, Shaanxi, 710061, People's Republic of China.
Gang TianDepartment of Cardiovascular Medicine, First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Rd, Xi'an, Shaanxi, 710061, People's Republic of China. tiangang@xjtu.edu.cn.
First Affiliated Hospital of Xi'an Jiaotong University · CN

Funding

The Nature Science Foundation of China Grant No. 81873513, 81600574, and 30871042
6 · The paper itself

Abstract

objectiveCurrent guidelines are debated when it comes to starting anticoagulant therapy in patients with non-valvular atrial fibrillation (NVAF) and low CHA

methodsNVAF patients with available transesophageal echocardiography (TEE) data were evaluated. Based on the TEE results, the subjects were classified into non-LAT/SEC and LAT/SEC groups. The risk factors for LAT/SEC were examined using binary logistic regression analyses and were validated by using 1:1 propensity score matching (PSM). Subsequently, novel predictive models for LAT/SEC were developed by integrating the CHA

resultsIn total, 481 NVAF patients were enrolled. The LAT/SEC group displayed higher Lp(a) concentrations. It was found that enlarged left atrial diameter (LAD), high concentrations of Lp(a), and a history of coronary heart disease (CHD) were independent predictors of LAT/SEC. Lp(a) and LAD still had predictive values for LAT/SEC after adjusting for PSM. In both the highest quartile groups of Lp(a) (>266 mg/L) and LAD (>39.5 mm), the occurrence of LAT/SEC was higher than that in the corresponding lowest quartile. By incorporating Lp(a) and the LAD, the predictive value of the CHA

conclusionElevated Lp(a) and enlarged LAD were independent risk factors for LAT/SEC among NVAF patients with low CHA

trial registrationRetrospectively registered.

Indexed as

Atrial FibrillationLipoprotein(a)ThrombosisCross-Sectional StudiesFemaleHumansMalePropensity ScoreLipoprotein(a)Atrial fibrillationCHA2DS2-VASc scoreLeft atrial spontaneous echo contrastLeft atrial thrombusLipoprotein(a)

Identifiers

PMID38254171
PMCPMC10801929
OpenAlexW4391110514

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.