ArticleCardiovascular diabetology2024
The relationship between triglyceride-glucose index and prospective key clinical outcomes in patients hospitalised for coronary artery disease.
Article in Cardiovascular diabetology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Comment on Li et al. Association of Triglyceride-Glucose Index and Coronary Chronic Total Occlusion in Patients Undergoing Coronary Angiography: A Retrospective Study.Journal of cardiovascular development and disease · 2026Article
- Observational
- The Association Between Triglyceride-Glucose Index and Mortality Risk in Cardiovascular Disease Patients: A Meta-Analysis.Journal of clinical medicine research · 2026Article
- Triglyceride glucose index and modified triglyceride glucose indices are instrumental to optimize 3P medical management for postpartum cardiovascular disease.The EPMA journal · 2026Article
- Nonlinear Association Between THs, TSH, and HbA1c in Patients With Type 2 Diabetes Mellitus: A Retrospective Study.Journal of diabetes · 2026Article
- Unveiling a J-shaped association between the triglyceride-glucose index and in-hospital major adverse cardiovascular events in patients with acute myocardial infarction: a retrospective cohort study of 1,065 patients.Frontiers in cardiovascular medicine · 2026Article
- Development and validation of a machine learning-based sarcopenia prediction model using the triglyceride glucose-frailty index.The Journal of international medical research · 2026Article
- Prognostic value of triglyceride-glucose index combined with stress hyperglycemia ratio for all-cause mortality in critically ill patients with stroke.Cardiovascular diabetology · 2025Article
- Association of VEGFA Gene Polymorphisms with the Susceptibility of Coronary Heart Disease in the Chinese Han Population.Cardiovascular toxicology · 2025Article
- Association between the triglyceride glucose index and long-term outcomes in patients with acute coronary syndrome and chronic kidney disease.Diabetology & metabolic syndrome · 2025Article
- Inflammatory storm and metabolic disorders: unraveling heterogeneity in mortality risk for comorbid diabetes mellitus and heart failure via the C-reactive protein-triglyceride-glucose index.Frontiers in endocrinology · 2025Article
- Independent and combined associations of high-density lipoprotein cholesterol-modified triglyceride-glucose index with all-cause and cardiovascular mortality in patients with acute decompensated heart failure.Frontiers in endocrinology · 2025Article
- The association between triglyceride glucose index and the risk of cardiovascular disease in obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2024Article
- Predictive value of the triglyceride-glucose index for short- and long-term all-cause mortality in patients with critical coronary artery disease: a cohort study from the MIMIC-IV database.Lipids in health and disease · 2024Article
- [A ssociations of short-term ambient particulate matter exposure andBeijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2024Article
- Changes in the combination of the triglyceride-glucose index and obesity indicators estimate the risk of cardiovascular disease.Cardiovascular diabetology · 2024Article
- The association between triglyceride-glucose index and gallstones: NHANES 2017-2020.Frontiers in endocrinology · 2024Article
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Abstract
backgroundThe triglyceride-glucose (TyG) index is regarded as a dependable alternative for assessing insulin resistance (IR), given its simplicity, cost-effectiveness, and strong correlation with IR. The relationship between the TyG index and adverse outcomes in patients with coronary heart disease (CHD) is not well established. This study examines the association of the TyG index with long-term adverse outcomes in hospitalized CHD patients.
methodsIn this single-center prospective cohort study, 3321 patients hospitalized with CHD were included. Multivariate Cox regression models were employed to assess the associations between the TyG index and the incidence of all-cause mortality and major adverse cardiovascular events (MACEs). To examine potential nonlinear associations, restricted cubic splines and threshold analysis were utilized.
resultsDuring a follow-up period of 9.4 years, 759 patients (22.9%) succumbed to mortality, while 1291 (38.9%) experienced MACEs. Threshold analysis demonstrated a significant "U"-shaped nonlinear relationship with MACEs, with different hazard ratios observed below and above a TyG index of 8.62 (below: HR 0.71, 95% CI 0.50-0.99; above: HR 1.28, 95% CI 1.10-1.48). Notably, an increased risk of all-cause mortality was observed only when the TyG index exceeded 8.77 (HR 1.53, 95% CI 1.19-1.96).
conclusionsThis study reveals a nonlinear association between the TyG index and both all-cause mortality and MACEs in hospitalized CHD patients with CHD. Assessing the TyG index, particularly focusing on individuals with extremely low or high TyG index values, may enhance risk stratification for adverse outcomes in this patient population.
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