Evidence map›Paper›PMID 38254025›Full record

ArticleBMC infectious diseases2024

An analysis of differences in Carbapenem-resistant Enterobacterales in different regions: a multicenter cross-sectional study.

Bo Guo, Peili Li, Bingyu Qin, Shanmei Wang, Wenxiao Zhang, Yuan Shi, Jianxu Yang, Jingjing Niu, Shifeng Chen, Xiao Chen and 26 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors.

Bo GuoDepartment of Critical Care Medicine, Henan Key Laboratory for Critical Care Medicine, Zhengzhou Key Laboratory for Critical Care Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China.
Peili LiDepartment of Public Utilities Development, Henan Provincial People's Hospital, Zhengzhou, China.
Bingyu QinDepartment of Critical Care Medicine, Henan Key Laboratory for Critical Care Medicine, Zhengzhou Key Laboratory for Critical Care Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China.
Shanmei WangDepartment of Microbiology Laboratory, Henan Provincial People's Hospital, Zhengzhou, China.
Wenxiao ZhangDepartment of Critical Care Medicine, Henan Key Laboratory for Critical Care Medicine, Zhengzhou Key Laboratory for Critical Care Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China.
Yuan ShiDepartment of Critical Care Medicine, Henan Key Laboratory for Critical Care Medicine, Zhengzhou Key Laboratory for Critical Care Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China.
Jianxu YangDepartment of Critical Care Medicine, Henan Key Laboratory for Critical Care Medicine, Zhengzhou Key Laboratory for Critical Care Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China.
Jingjing NiuDepartment of Critical Care Medicine, Henan Key Laboratory for Critical Care Medicine, Zhengzhou Key Laboratory for Critical Care Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China.
Shifeng ChenDepartment of Critical Care Medicine, The Second People's Hospital of Pingdingshan City, Pingdingshan, China.
Xiao ChenDepartment of Critical Care Medicine, Nanyang Nanshi Hospital, Nanyang, China.
Lin CuiDepartment of Critical Care Medicine, Yellow River Central Hospital, Zhengzhou, China.
Qizhi FuDepartment of Critical Care Medicine, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang, China.
Lin GuoDepartment of Critical Care Medicine, The Seventh People's Hospital of Zhengzhou, Zhengzhou, China.
Zhe HouDepartment of Critical Care Medicine, Zhengzhou Orthopedic Hospital, Zhengzhou, China.
Hua LiDepartment of Critical Care Medicine, Henan Provincial Hospital of Traditional Chinese Medicine, Zhengzhou, China.
Xiaohui LiDepartment of Critical Care Medicine, Fuwai Central China Cardiovascular Hospital, Zhengzhou, China.
Ruifang LiuDepartment of Critical Care Medicine, The Third People's Hospital of Henan Province, Zhengzhou, China.
Xiaojun LiuDepartment of Critical Care Medicine, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhengrong MaoDepartment of Critical Care Medicine, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
Xingguo NiuDepartment of Critical Care Medicine, Zhengzhou People's Hospital, Zhengzhou, 450000, China.
Chao QinDepartment of Critical Care Medicine, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xianrong SongDepartment of Critical Care Medicine, Henan Provincial Chest Hospital, Zhengzhou, China.
Rongqing SunDepartment of Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Tongwen SunDepartment of Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Daoxie WangDepartment of Critical Care Medicine, The Third People's Hospital of Zhengzhou, Zhengzhou, China.
Yong WangDepartment of Critical Care Medicine, Huaihe Hospital of Henan University, Kaifeng, China.
Lanjuan XuDepartment of Critical Care Medicine, Zhengzhou Central Hospital, Zhengzhou, China.
Xin XuDepartment of Critical Care Medicine, The First Affiliated Hospital of Henan University, Kaifeng, China.
Yuejie YangDepartment of Critical Care Medicine, The Sixth People's Hospital of Zhengzhou, Zhengzhou, China.
Baoquan ZhangDepartment of Critical Care Medicine, The Third Affiliated Hospital of Xinxiang Medical College, Xinxiang, China.
Dongmin ZhouDepartment of Critical Care Medicine, Henan Cancer Hospital, Zhengzhou, China.
Zhaozhen LiDepartment of Critical Care Medicine, Henan Provincial Chest Hospital, Zhengzhou, China.
Yinyin ChenDepartment of Critical Care Medicine, Henan Key Laboratory for Critical Care Medicine, Zhengzhou Key Laboratory for Critical Care Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China.
Yue JinDepartment of Critical Care Medicine, Henan Key Laboratory for Critical Care Medicine, Zhengzhou Key Laboratory for Critical Care Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China.
Juan DuDepartment of Critical Care Medicine, Henan Key Laboratory for Critical Care Medicine, Zhengzhou Key Laboratory for Critical Care Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China.
Huanzhang ShaoDepartment of Critical Care Medicine, Henan Key Laboratory for Critical Care Medicine, Zhengzhou Key Laboratory for Critical Care Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, China. shaohuanzhang001@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to explore the characteristics of carbapenem-resistant Enterobacterales (CRE) patients in the intensive care unit (ICU) in different regions of Henan Province to provide evidence for the targeted prevention and treatment of CRE.

methodsThis was a cross-sectional study. CRE screening was conducted in the ICUs of 78 hospitals in Henan Province, China, on March 10, 2021. The patients were divided into provincial capital hospitals and nonprovincial capital hospitals for comparative analysis.

resultsThis study involved 1009 patients in total, of whom 241 were CRE-positive patients, 92 were in the provincial capital hospital and 149 were in the nonprovincial capital hospital. Provincial capital hospitals had a higher rate of CRE positivity, and there was a significant difference in the rate of CRE positivity between the two groups. The body temperature; immunosuppressed state; transfer from the ICU to other hospitals; and use of enemas, arterial catheters, carbapenems, or tigecycline at the provincial capital hospital were greater than those at the nonprovincial capital hospital (P < 0.05). However, there was no significant difference in the distribution of carbapenemase strains or enzymes between the two groups.

conclusionsThe detection rate of CRE was significantly greater in provincial capital hospitals than in nonprovincial capital hospitals. The source of the patients, invasive procedures, and use of advanced antibiotics may account for the differences. Carbapenem-resistant Klebsiella pneumoniae (CR-KPN) was the most prevalent strain. Klebsiella pneumoniae carbapenemase (KPC) was the predominant carbapenemase enzyme. The distributions of carbapenemase strains and enzymes were similar in different regions.

Indexed as

Anti-Bacterial AgentsBody TemperatureCannulaCarbapenemsCross-Sectional StudiesHumansKlebsiella pneumoniaeAnti-Bacterial AgentsCarbapenemsBacterialDrug resistanceGeographic locationIntensive care unitsPrevalence

Identifiers

PMID38254025
PMCPMC10804584

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