Evidence map›Paper›PMID 38253917›Full record

ReviewAAPS PharmSciTech2024

Insights into Translational and Biomedical Applications of Hydrogels as Versatile Drug Delivery Systems.

Ramesh Kohar, Maitrayee Ghosh, Jyotiram A Sawale, Amandeep Singh, Naresh Kumar Rangra, Rohit Bhatia

Abstract readReview
PubMed Publisher
In one paragraph

Review in AAPS PharmSciTech, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ramesh KoharDepartment of Pharmaceutical Analysis & Chemistry, ISF College of Pharmacy, Moga, Punjab, 142001, India.
Maitrayee GhoshDepartment of Pharmaceutics, ISF College of Pharmacy, Moga, Punjab, 142001, India.
Jyotiram A SawaleDepartment of Pharmacognosy, Krishna Institute of Pharmacy, Krishna Vishwa Vidyapeeth (Deemed to Be University), Karad, 415539, Maharashtra, India.
Amandeep SinghDepartment of Pharmaceutics, ISF College of Pharmacy, Moga, Punjab, 142001, India.
Naresh Kumar RangraDepartment of Pharmaceutical Analysis & Chemistry, ISF College of Pharmacy, Moga, Punjab, 142001, India.
Rohit BhatiaDepartment of Pharmaceutical Analysis & Chemistry, ISF College of Pharmacy, Moga, Punjab, 142001, India. bhatiarohit5678@gmail.com.ORCID http://orcid.org/0000-0003-4194-8749

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogels are a network of crosslinked polymers which can hold a huge amount of water in their matrix. These might be soft, flexible, and porous resembling living tissues. The incorporation of different biocompatible materials and nanostructures into the hydrogels has led to emergence of multifunctional hydrogels with advanced properties. There are broad applications of hydrogels such as tissue culture, drug delivery, tissue engineering, implantation, water purification, and dressings. Besides these, it can be utilized in the field of medical surgery, in biosensors, targeted drug delivery, and drug release. Similarly, hyaluronic acid hydrogels have vast applications in biomedicines such as cell delivery, drug delivery, molecule delivery, micropatterning in cellular biology for tissue engineering, diagnosis and screening of diseases, tissue repair and stem cell microencapsulation in case of inflammation, angiogenesis, and other biological developmental processes. The properties like swellability, de-swellability, biodegradability, biocompatibility, and inert nature of the hydrogels in contact with body fluids, blood, and tissues make its tremendous application in the field of modern biomedicines nowadays. Various modifications in hydrogel formulations have widened their therapeutic applicability. These include 3D printing, conjugation, thiolation, multiple anchoring, and reduction. Various hydrogel formulations are also capable of dual drug delivery, dental surgery, medicinal implants, bone diseases, and gene and stem cells delivery. The presented review summarizes the unique properties of hydrogels along with their methods of preparation and significant biomedical applications as well as different types of commercial products available in the market and the regulatory guidance.

Indexed as

Body FluidsDrug Delivery SystemsBandagesBiocompatible MaterialsHydrogelsBiocompatible MaterialsHydrogelsbiomedicinesbone defectscrosslinkingdrug deliveryhyaluronic acidhydrogelspolymers

Identifiers

PMID38253917

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.