Evidence map›Paper›PMID 38253890›Full record

ArticleCell and tissue research2024

Rheb1 is required for limb growth through regulating chondrogenesis in growth plate.

Yuwei Zhang, Jiaxin Wen, Ruijun Lai, Jiahuan Zhang, Kai Li, Yue Zhang, Anling Liu, Xiaochun Bai

Open access · hybridAbstract read
In one paragraph

Article in Cell and tissue research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yuwei ZhangSchool of Basic Medical Science, Southern Medical University, Guangzhou, Guangdong, 510515, People's Republic of China.
Jiaxin WenSchool of Basic Medical Science, Southern Medical University, Guangzhou, Guangdong, 510515, People's Republic of China.
Ruijun LaiThe Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, 510515, People's Republic of China.
Jiahuan ZhangLaboratory Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510000, People's Republic of China.
Kai LiThe Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, 510515, People's Republic of China.
Yue ZhangSchool of Basic Medical Science, Southern Medical University, Guangzhou, Guangdong, 510515, People's Republic of China. yugi@smu.edu.cn.
Anling LiuSchool of Basic Medical Science, Southern Medical University, Guangzhou, Guangdong, 510515, People's Republic of China. aliu@smu.edu.cn.
Xiaochun BaiSchool of Basic Medical Science, Southern Medical University, Guangzhou, Guangdong, 510515, People's Republic of China. baixc15@smu.edu.cn.ORCID http://orcid.org/0000-0001-9631-4781
Southern Medical University · CNThird Affiliated Hospital of Southern Medical University · CNGuangdong Academy of Medical Sciences · CN

Funding

National Natural Science Foundation of China 81871745
6 · The paper itself

Abstract

Ras homology enriched in the brain (Rheb) is well established as a critical regulator of cell proliferation and differentiation in response to growth factors and nutrients. However, the role of Rheb1 in limb development remains unknown. Here, we found that Rheb1 was dynamically expressed during the proliferation and differentiation of chondrocytes in the growth plate. Given that Prrx1

Indexed as

ChondrogenesisGrowth PlateAnimalsCartilageCell DifferentiationChondrocytesMiceOsteogenesisRas Homolog Enriched in Brain ProteinRas Homolog Enriched in Brain ProteinRheb protein, mouseChondrocyte maturationChondrocyte ProliferationChondrogenesismTORC1Rheb1

Identifiers

PMID38253890
PMCPMC10904423
OpenAlexW4391116658

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.