ArticleNature methods2024
An improved pathway for autonomous bioluminescence imaging in eukaryotes.
Article in Nature methods, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- When plants light up: fungal bioluminescence pathway-based sentinel systems for autonomous virus diagnostics.aBIOTECH · 2026Article
- Caffeylpyruvate hydrolase from the bioluminescent fungus Neonothopanus gardneri is the key recycling enzyme in the fungal bioluminescence pathway.The FEBS journal · 2026Article
- Visualisation and Prediction of Phosphate Deficiency via Auto-Glowing Plant Bioluminescent Sensors.Plant, cell & environment · 2026Article
- Expanding agroinfiltration host range with broad-spectrum effectors monitored by autoluminescent reporter.Horticulture research · 2026Article
- Bioluminescence in the Edible MushroomJournal of fungi (Basel, Switzerland) · 2026Article
- Bioluminescent sentinel plants enable autonomous diagnostics of viral infections.Nature communications · 2026Article
- The Promise of Synthetic Biology for Redesigning Plant Architecture.International journal of molecular sciences · 2026Review
- Non-invasive imaging of defence responses in plants.Nature communications · 2026Article
- Sustainable bioenergy manufacturing in plants.Plant communications · 2026Review
- Transgenic Tobacco as a Bioreactor for the Production of Bioactive and Triple-Helical Recombinant Type III Collagen.Plants (Basel, Switzerland) · 2026Article
- Advances in luminescence-based tracing technologies: applications and future perspectives.Biodesign research · 2026Review
- Synthetic Biology of Plants and Microbes for Agriculture, Environment, and Future Applications.Chemical reviews · 2026Review
- Protein engineering: status report.Protein engineering, design & selection : PEDS · 2026Review
- Engineering glowing plants: recent progress and future directions for application-oriented design.Frontiers in bioengineering and biotechnology · 2026Review
- Establishment and maintenance of NRT2.1 inter-individual variability in plants.PLoS genetics · 2025Article
- Autonomous Bioluminescence Systems: From Molecular Mechanisms to Emerging Applications.JACS Au · 2025Review
- Synthesis of large single-transcript pathways from oligonucleotide pools: Design of STARBURST, an autobioluminescent reporter.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Conserved and Specific Root-Associated Microbiome Reveals Close Correlation Between Fungal Community and Growth Traits of Multiple Chinese Fir Genotypes.Microorganisms · 2025Article
- Expression of a multigene mushroom luciferin biosynthesis pathway as a pseudo-polycistron in plants.Scientific reports · 2025Article
- Development of an FBP-based bioluminescence reporter system for investigating transcriptional regulation in plants.Plant communications · 2025Article
Corrections and comments
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Authors and funding
26 authors.
Funding
Abstract
The discovery of the bioluminescence pathway in the fungus Neonothopanus nambi enabled engineering of eukaryotes with self-sustained luminescence. However, the brightness of luminescence in heterologous hosts was limited by performance of the native fungal enzymes. Here we report optimized versions of the pathway that enhance bioluminescence by one to two orders of magnitude in plant, fungal and mammalian hosts, and enable longitudinal video-rate imaging.
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Registered trials
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