Evidence map›Paper›PMID 38253738›Full record

ArticleNPJ digital medicine2024

Diagnostic performance of artificial intelligence-assisted PET imaging for Parkinson's disease: a systematic review and meta-analysis.

Jing Wang, Le Xue, Jiehui Jiang, Fengtao Liu, Ping Wu, Jiaying Lu, Huiwei Zhang, Weiqi Bao, Qian Xu, Zizhao Ju and 6 more

Open access · goldAbstract read
In one paragraph

Article in NPJ digital medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 4 pooled it
14.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Detection of parkinson's disease with neuroimaging modalities using machine learning and artificial intelligence: a systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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  12. Baseline [NPJ Parkinson's disease · 2025
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  13. Cross-modality PET image synthesis for Parkinson's Disease diagnosis: a leap from [European journal of nuclear medicine and molecular imaging · 2025
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  16. Biomarker-Based Approach to α-Synucleinopathies: Lessons from Neuropathology.Movement disorders : official journal of the Movement Disorder Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Jing WangHuashan Hospital & Human Phenome Institute, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0003-2445-4966
Le XueDepartment of Nuclear Medicine, the Second Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.ORCID http://orcid.org/0000-0002-9627-0763
Jiehui JiangInstitute of Biomedical Engineering, School of Life Science, Shanghai University, Shanghai, China.ORCID http://orcid.org/0000-0003-4948-3683
Fengtao LiuDepartment of Neurology, Huashan Hospital, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0001-7688-1631
Ping WuDepartment of Nuclear Medicine/PET Center, Huashan Hospital, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0002-2758-1218
Jiaying LuDepartment of Nuclear Medicine/PET Center, Huashan Hospital, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0003-0927-0042
Huiwei ZhangDepartment of Nuclear Medicine/PET Center, Huashan Hospital, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0002-1509-2249
Weiqi BaoDepartment of Nuclear Medicine/PET Center, Huashan Hospital, Fudan University, Shanghai, China.
Qian XuDepartment of Nuclear Medicine/PET Center, Huashan Hospital, Fudan University, Shanghai, China.
Zizhao JuDepartment of Nuclear Medicine/PET Center, Huashan Hospital, Fudan University, Shanghai, China.
Li ChenDepartment of Ultrasound Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Fangyang JiaoDepartment of Nuclear Medicine/PET Center, Huashan Hospital, Fudan University, Shanghai, China.
Huamei LinDepartment of Nuclear Medicine/PET Center, Huashan Hospital, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0002-6851-2366
Jingjie GeDepartment of Nuclear Medicine/PET Center, Huashan Hospital, Fudan University, Shanghai, China. lovejingjie@126.com.ORCID http://orcid.org/0000-0001-6413-5914
Chuantao ZuoHuashan Hospital & Human Phenome Institute, Fudan University, Shanghai, China. zuochuantao@fudan.edu.cn.ORCID http://orcid.org/0000-0002-8856-7217
Mei TianHuashan Hospital & Human Phenome Institute, Fudan University, Shanghai, China. tianmei@fudan.edu.cn.ORCID http://orcid.org/0000-0002-1587-2114
Fudan University · CNSecond Affiliated Hospital of Zhejiang University · CNShanghai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial intelligence (AI)-assisted PET imaging is emerging as a promising tool for the diagnosis of Parkinson's disease (PD). We aim to systematically review the diagnostic accuracy of AI-assisted PET in detecting PD. The Ovid MEDLINE, Ovid Embase, Web of Science, and IEEE Xplore databases were systematically searched for related studies that developed an AI algorithm in PET imaging for diagnostic performance from PD and were published by August 17, 2023. Binary diagnostic accuracy data were extracted for meta-analysis to derive outcomes of interest: area under the curve (AUC). 23 eligible studies provided sufficient data to construct contingency tables that allowed the calculation of diagnostic accuracy. Specifically, 11 studies were identified that distinguished PD from normal control, with a pooled AUC of 0.96 (95% CI: 0.94-0.97) for presynaptic dopamine (DA) and 0.90 (95% CI: 0.87-0.93) for glucose metabolism (

Identifiers

PMID38253738
PMCPMC10803804
OpenAlexW4391102926

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.