Evidence map›Paper›PMID 38253543›Full record

ArticleTranslational psychiatry2024

Altered dynamic functional and effective connectivity in drug-naive children with Tourette syndrome.

Lekai Luo, Yi Liao, Fenglin Jia, Gang Ning, Jing Liu, Xuesheng Li, Xijian Chen, Xinmao Ma, Xuejia He, Chuan Fu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Translational psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Lekai Luo *Department of Radiology, West China Second University Hospital, Sichuan University, Chengdu, 610021, Sichuan, PR China.ORCID 0000-0003-2502-7595
Yi Liao *Department of Radiology, West China Second University Hospital, Sichuan University, Chengdu, 610021, Sichuan, PR China.ORCID 0000-0001-8926-8692
Fenglin JiaDepartment of Radiology, West China Second University Hospital, Sichuan University, Chengdu, 610021, Sichuan, PR China.
Gang NingDepartment of Radiology, West China Second University Hospital, Sichuan University, Chengdu, 610021, Sichuan, PR China.
Jing LiuDepartment of Radiology, West China Second University Hospital, Sichuan University, Chengdu, 610021, Sichuan, PR China.
Xuesheng LiDepartment of Radiology, West China Second University Hospital, Sichuan University, Chengdu, 610021, Sichuan, PR China.
Xijian ChenDepartment of Radiology, West China Second University Hospital, Sichuan University, Chengdu, 610021, Sichuan, PR China.
Xinmao MaDepartment of Radiology, West China Second University Hospital, Sichuan University, Chengdu, 610021, Sichuan, PR China.
Xuejia HeDepartment of Radiology, West China Second University Hospital, Sichuan University, Chengdu, 610021, Sichuan, PR China.
Chuan FuDepartment of Radiology, West China Second University Hospital, Sichuan University, Chengdu, 610021, Sichuan, PR China.
Xiaotang CaiKey Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, 610021, Sichuan, PR China. cxt_1999@126.com.ORCID 0000-0001-8940-8253
Haibo QuDepartment of Radiology, West China Second University Hospital, Sichuan University, Chengdu, 610021, Sichuan, PR China. windowsqhb@126.com.ORCID 0000-0003-0481-4856
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tourette syndrome (TS) is a developmental neuropsychiatric disorder characterized by repetitive, stereotyped, involuntary tics, the neurological basis of which remains unclear. Although traditional resting-state MRI (rfMRI) studies have identified abnormal static functional connectivity (FC) in patients with TS, dynamic FC (dFC) remains relatively unexplored. The rfMRI data of 54 children with TS and 46 typically developing children (TDC) were analyzed using group independent component analysis to obtain independent components (ICs), and a sliding-window approach to generate dFC matrices. All dFC matrices were clustered into two reoccurring states, the state transition metrics were obtained. We conducted Granger causality and nodal topological analyses to further investigate the brain regions that may play the most important roles in driving whole-brain switching between different states. We found that children with TS spent more time in state 2 (P

Indexed as

Tourette SyndromeBrainChildExecutive FunctionHumansStereotyped Behavior

Identifiers

PMID38253543
PMCPMC10803732
OpenAlexW4391098306

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.