Evidence map›Paper›PMID 38253521›Full record

ArticlePalliative medicine2024

Social acceptability of psilocybin-assisted therapy for existential distress at the end of life: A population-based survey.

Louis Plourde, Sue-Ling Chang, Houman Farzin, Pierre Gagnon, Johanne Hébert, Robert Foxman, Pierre Deschamps, François Provost, Marianne Masse-Grenier, Jean-François Stephan and 5 more

Abstract read
In one paragraph

Article in Palliative medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. A Rapid Review of Psychedelic-Assisted Therapy in the Context of Palliative Care.Journal of hospice and palliative nursing : JHPN : the official journal of the Hospice and Palliative Nurses Association · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. "Integrative cancer therapies
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Louis PlourdeFaculty of Pharmacy, Université Laval, Québec City, QC, Canada.
Sue-Ling ChangCHU de Québec-Université Laval Research Center, Oncology Division, Québec City, QC, Canada.
Houman FarzinLady Davis Institute for Medical Research, Jewish General Hospital, Montréal, QC, Canada.
Pierre GagnonCHU de Québec-Université Laval Research Center, Oncology Division, Québec City, QC, Canada.
Johanne HébertDepartment of Health Sciences, UQAR, Lévis, Rimouski, QC, Canada.
Robert FoxmanPatient Partner, Montréal, QC, Canada.
Pierre DeschampsCommission sur les soins de fin de vie, Montréal, QC, Canada.
François ProvostCHU de Québec-Université Laval Research Center, Oncology Division, Québec City, QC, Canada.
Marianne Masse-GrenierFaculty of Pharmacy, Université Laval, Québec City, QC, Canada.
Jean-François StephanInstitut universitaire en santé mentale de Montréal, Montréal, QC, Canada.
Katherine CheungDepartment of Bioethics, New York University, New York, NY, USA.
Yann JolyFaculty of Medicine and Health Sciences, McGill University, Montréal, QC, Canada.
Jean-Sébastien FalluSchool of Psychoeducation, Université de Montréal, Montréal, QC, Canada.
Michel DorvalFaculty of Pharmacy, Université Laval, Québec City, QC, Canada.ORCID 0000-0002-3207-8211
P3A Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInternationally, there is a growing interest in the potential benefits of psilocybin-assisted therapy to treat existential distress at the end of life. However, the social acceptability of this therapy is not yet well known.

aimThis study assesses the social acceptability of the medical use of psilocybin to treat existential distress at the end of life.

designAn online survey was conducted in Canada between November 23 and December 4, 2022. The questionnaire included items pertaining to perceptions, attitudes and concerns towards psilocybin-assisted therapy to treat existential distress at the end of life.

participantsThe sample (

resultsOverall, 79.3% considered psilocybin-assisted therapy a reasonable medical choice for a patient suffering from existential distress at the end of life, 84.8% agreed that the public health system should cover the costs of the intervention and 63.3% would welcome the legalisation of psilocybin for medical purposes. Previous psilocybin use (

conclusionThe social acceptability of psilocybin-assisted therapy for existential distress at the end of life is rather high in Canada. These findings may contribute to efforts to mobilise resources and improve access to this emerging therapy in palliative and end of life care settings.

Indexed as

PsilocybinTerminal CareAdultAlbertaDeathHumansPalliative CarePsilocybinend-of-lifepalliative carePsilocybinpsychedelicpsychological distresspublic opinionsurvey

Identifiers

PMID38253521
PMCPMC10865753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.