ReviewEndocrinology and metabolism (Seoul, Korea)2024
A Contemporary Approach to the Diagnosis and Management of Adrenal Insufficiency.
Review in Endocrinology and metabolism (Seoul, Korea), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Metabolic Effects of Modified-Release Hydrocortisone Versus Short Acting Conventional Oral Glucocorticoids in Adrenal Insufficiency: A Systematic Review and Meta-Analysis.Clinical endocrinology · 2026Pooled it
- Adrenal Insufficiency in Patients with Beta Thalassemia: A Meta-Analysis.Medicina (Kaunas, Lithuania) · 2024Pooled it
- Hyponatremia as the Initial Presentation of Rathke's Cleft Cyst-Related Hypopituitarism.Cureus · 2026Article
- Hemodynamic management, including for left ventricular outflow tract obstruction, in an infant with ACTH-independent Cushing syndrome undergoing adrenal tumor removal: a case report.JA clinical reports · 2026Article
- Two contrasting cases of adrenal insufficiency in adults: a case report.Journal of medical case reports · 2026Article
- Article
- Post-ACTH peak cortisol response is associated with genotype in children with nonclassic congenital adrenal hyperplasia.Frontiers in endocrinology · 2026Article
- Unintentional discontinuation of topical corticosteroids after emergency hospitalization can exacerbate adrenal insufficiency.Endocrine journal · 2025Article
- Management of Primary Adrenal Insufficiency and Overt Hypothyroidism in an HIV-Positive Patient in a Resource-Limited Setting: A Case Report.Clinical case reports · 2025Article
- Article
- A deep learning algorithm for automated adrenal gland segmentation on non-contrast CT images.BMC medical imaging · 2025Article
- The Effect of Whitening Creams Usage on the Adrenal Gland .F1000Research · 2025Article
- BASAL MORNING CORTISOL IN PATIENTS REFERRED FOR ACTH STIMULATION TESTING: DIAGNOSTIC PERFORMANCE IN A RETROSPECTIVE COHORT.Acta endocrinologica (Bucharest, Romania : 2005)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adrenal insufficiency (AI) can be classified into three distinct categories based on its underlying causes: primary adrenal disorders, secondary deficiencies in adrenocorticotropin, or hypothalamic suppression from external factors, most commonly glucocorticoid medications used for anti-inflammatory therapy. The hallmark clinical features of AI include fatigue, appetite loss, unintentional weight loss, low blood pressure, and hyponatremia. Individuals with primary AI additionally manifest skin hyperpigmentation, hyperkalemia, and salt craving. The diagnosis of AI is frequently delayed due to the non-specific symptoms and signs early in the disease course, which poses a significant challenge to its early detection prior to an adrenal crisis. Despite the widespread availability of lifesaving glucocorticoid medications for decades, notable challenges persist, particularly in the domains of timely diagnosis while simultaneously avoiding misdiagnosis, patient education for averting adrenal crises, and the determination of optimal replacement therapies. This article reviews recent advancements in the contemporary diagnostic strategy and approaches to optimal treatment for AI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.