Evidence map›Paper›PMID 38253415›Full record

ReviewCold Spring Harbor perspectives in biology2024

Fisher's Geometric Model as a Tool to Study Speciation.

Hilde Schneemann, Bianca De Sanctis, John J Welch

Open access · greenAbstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Genetics and genomics of hybridization.Nature reviews. Genetics · 2026
    Review
  2. Quantitative system drift.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. The Ecology of Hybrid Incompatibilities.Cold Spring Harbor perspectives in biology · 2024
    Review
  5. Review
  6. Coupling of Barriers to Gene Exchange: Causes and Consequences.Cold Spring Harbor perspectives in biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hilde SchneemannDepartment of Genetics, University of Cambridge, Cambridge CB2 3EH, United Kingdom hilde.schneemann@evobio.eu.
Bianca De SanctisDepartment of Genetics, University of Cambridge, Cambridge CB2 3EH, United Kingdom.
John J WelchDepartment of Genetics, University of Cambridge, Cambridge CB2 3EH, United Kingdom.
University of Cambridge · GB

Funding

Wellcome Trust 220023
6 · The paper itself

Abstract

Interactions between alleles and across environments play an important role in the fitness of hybrids and are at the heart of the speciation process. Fitness landscapes capture these interactions and can be used to model hybrid fitness, helping us to interpret empirical observations and clarify verbal models. Here, we review recent progress in understanding hybridization outcomes through Fisher's geometric model, an intuitive and analytically tractable fitness landscape that captures many fitness patterns observed across taxa. We use case studies to show how the model parameters can be estimated from different types of data and discuss how these estimates can be used to make inferences about the divergence history and genetic architecture. We also highlight some areas where the model's predictions differ from alternative incompatibility-based models, such as the snowball effect and outlier patterns in genome scans.

Indexed as

Genetic SpeciationAnimalsGenetic FitnessHybridization, GeneticModels, Genetic

Identifiers

PMID38253415
PMCPMC11216183
OpenAlexW4391098983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.