Evidence map›Paper›PMID 38252764›Full record

ArticleStroke2024

New Picture Stimuli for the NIH Stroke Scale: A Validation Study.

Melissa D Stockbridge, Lindsey Kelly, Sarah Newman-Norlund, Brian White, Marianne Bourgeois, Elizabeth Rothermel, Julius Fridriksson, Patrick D Lyden, Argye E Hillis

Open access · bronzeAbstract read
In one paragraph

Article in Stroke, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Revisiting Western Aphasia Battery-Revised in the Context of Mild Impairment.American journal of speech-language pathology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Melissa D StockbridgeDepartment of Neurology (M.D.S., L.K., A.E.H.), Johns Hopkins University School of Medicine, Baltimore, MD.ORCID 0000-0001-9069-1236
Lindsey KellyDepartment of Neurology (M.D.S., L.K., A.E.H.), Johns Hopkins University School of Medicine, Baltimore, MD.
Sarah Newman-NorlundDepartment of Communication Sciences and Disorders, Arnold School of Public Health, University of South Carolina, Columbia (S.N.-N., J.F.).ORCID 0000-0002-9064-1332
Brian WhiteApex Innovations LLC, Lafayette, LA (B.W., M.B., E.R.).ORCID 0009-0005-4374-4100
Marianne BourgeoisApex Innovations LLC, Lafayette, LA (B.W., M.B., E.R.).ORCID 0009-0009-4909-3993
Elizabeth RothermelApex Innovations LLC, Lafayette, LA (B.W., M.B., E.R.).ORCID 0009-0009-6116-095X
Julius FridrikssonDepartment of Communication Sciences and Disorders, Arnold School of Public Health, University of South Carolina, Columbia (S.N.-N., J.F.).
Patrick D LydenDepartment of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine of University of Southern California, Los Angeles (P.D.L.).ORCID 0000-0001-6170-4042
Argye E HillisDepartment of Neurology (M.D.S., L.K., A.E.H.), Johns Hopkins University School of Medicine, Baltimore, MD.ORCID 0000-0002-5192-1171
Johns Hopkins University · USUniversity of South Carolina · USAdvanced Process Combinatorics (United States) · USIDEXX Laboratories (France) · FRUniversity Hospital and Clinics · USUniversity of Southern California · US

Funding

Telerehab for Aphasia (TERRA)P50DC014664 · NIDCD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI BONILHA, LEONARDO F · 2016 to 2025
$25.0M
Neural Basis of Lexical Deficits in Hyperacute StrokeR01DC005375 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI Argye E. Hillis · 2002 to 2026
$11.8M
Trans-cranial Direct Current Stimulation to Treat Aphasia: Phase II TrialU01DC011739 · NIDCD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI FRIDRIKSSON, JULIUS · 2012 to 2016
$4.4M
ZZ-3K3A-301: A multicenter, randomized, placebo-controlled, double-blinded, Phase 3 study to evaluate the efficacy and safety of 3K3A-APC (RHAPSODY-2)UG3NS119199 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LYDEN, PATRICK D · 2022 to 2022
$4.0M
The Neural Basis of Impaired Affective Prosody in Alzheimer's Disease and Frontotemporal DegenerationR01DC015466 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI HILLIS, ARGYE E. · 2017 to 2021
$3.5M
The NIH SPAN Coordinating CenterU24NS130600 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LYDEN, PATRICK D · 2023 to 2025
$2.8M
NIDCD NIH HHS P50 DC014664NIDCD NIH HHS R01 DC005375NIDCD NIH HHS R01 DC015466NIDCD NIH HHS U01 DC011739NINDS NIH HHS U24 NS130600NINDS NIH HHS UG3 NS119199
6 · The paper itself

Abstract

backgroundThe National Institutes of Health Stroke Scale is a widely accepted tool for structured graded neurological examination of stroke or suspected stroke in the hyperacute setting. Concerns have arisen about the use of its picture stimuli in a contemporary and global health context. Here, we present new stimuli prepared to serve the needs of stroke providers worldwide: the precarious painter image description and updated objects for naming.

methodsThis was a validation study of 101 healthy fluent English speakers. Participants were reached by the Johns Hopkins Outpatient Center, the University of South Carolina, and Prisma Health from 2022 to 2023 and included residents of the United States, Germany, Canada, the United Kingdom, Australia, and Zambia. Participants were recorded in person or via video conferencing when asked to describe the new picture, while a subset named seven illustrations. Multivariate analyses of variance were used for primary analyses. In a complementary investigation, 299 attendees of the 2023 International Stroke Conference were asked about their preference for the existing or new stimuli and why.

resultsEach of the 44 content units from the picture description was included by at least 5% of respondents in the demographically representative subsample. Performance was similar across healthy participants irrespective of age, sex, race, ethnicity, or education. Typical descriptions were characterized by an average of 23 content units (SD=5) conveyed with 167 syllables (SD=79). The new naming stimuli were recognized by 100% of participants from many countries as being familiar and identifiable, and names provided in response to the task were highly convergent. The majority of stroke health care providers preferred both the precarious painter and naming stimuli.

conclusionsThe description of the new National Institutes of Health Stroke Scale picture, the precarious painter, results in rich samples among healthy speakers that will provide an appropriate basis for the detection of language deficits.

Indexed as

EthnicityStrokeAustraliaCanadaEducational StatusHumansadultaphasiacommunicationlanguagelanguage testssurveys and questionnaires

Identifiers

PMID38252764
PMCPMC10832390
OpenAlexW4391123140

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.