Evidence map›Paper›PMID 38252304›Full record

ArticleArchives of gynecology and obstetrics2024

Non-tubal ectopic pregnancy treatment experiences of a tertiary care center.

Yıldız Akdaş Reis, Arife Akay, Merve Özkan, Seval Yılmaz Ergani, Sadullah Özkan, Tuğba Kınay, Salim Erkaya

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Article in Archives of gynecology and obstetrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yıldız Akdaş ReisDepartment of Obstetrics and Gynecology, Etlik Zübeyde Hanım Maternity and Women's Health Teaching and Research Hospital, Ankara, Turkey. yildizakdasreis@hotmail.com.ORCID 0000-0001-9345-6899
Arife AkayDepartment of Obstetrics and Gynecology, Etlik Zübeyde Hanım Maternity and Women's Health Teaching and Research Hospital, Ankara, Turkey.ORCID 0000-0001-9640-2714
Merve ÖzkanDepartment of Perinatology, Etlik City Hospital, Ankara, Turkey.ORCID 0000-0002-3344-2804
Seval Yılmaz ErganiDepartment of Perinatology, Etlik City Hospital, Ankara, Turkey.ORCID 0000-0002-7017-8854
Sadullah ÖzkanDepartment of Perinatology, Etlik City Hospital, Ankara, Turkey.ORCID 0000-0003-2432-1434
Tuğba KınayDepartment of Obstetrics and Gynecology, Etlik Zübeyde Hanım Maternity and Women's Health Teaching and Research Hospital, Ankara, Turkey.ORCID 0000-0001-5340-1025
Salim ErkayaDepartment of Obstetrics and Gynecology, Bilkent City Hospital, Ankara, Turkey.ORCID 0000-0003-0331-952X
Zübeyde Hanim Maternity Hospital · TRBilkent University · TRBingöl University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the incidence, the risk factors, and the treatment outcomes of Non-tubal ectopic pregnancies (NTEP) treated in a tertiary care center. MATERIAL AND

methodsA total of 110 NTEP cases treated between 2014 and 2019 were included in the retrospective study. The study cohort was divided into 6 groups according to the pregnancy localization: 87 cesarean scar pregnancies (CSPs), 7 ovarian pregnancies, 6 interstitial pregnancies, 4 rudimentary horn pregnancies, 4 abdominal pregnancies, and 2 cervical pregnancies. One woman rejected all treatment modalities. Demographic characteristics, treatment modalities, and outcomes of each group were evaluated.

resultsIn the study cohort, expectant management was performed in one (0.9%) woman. The methotrexate (MTX) treatment was administered in 29 (26.3%) women. Seventeen (15.4%) women underwent surgery, and 63 (57.2%) women underwent manual vacuum aspiration (MVA). A woman rejected all treatment modalities. Although 70.1% (n = 61) of CSPs were cured with MVA, 24.1% (n = 21) of them were treated with a single-dose MTX regimen in addition to MVA. The higher mean gestational sac size (33,9 ± 12,96 mm vs. 17,34 ± 9,87 mm), the higher mean gestational week (8,43 ± 1,16w vs. 6,66 ± 1,49w), the presence of fetal heartbeat (FHB) (90.5% vs. 26,2%) and the history of pelvic ınflammatory disease (PID) (38.1% vs. 6,6%) were found in the CSPs with MVA treatment failure (p < 0.05).

conclusionThe management of NTEPs should be individualized according to the clinical and ultrasonographic findings. The size of the ectopic pregnancy mass, the gestational week, the presence of FHB, and the PID history were the predictive factors for the failure of MVA in CSP cases.

Indexed as

Abortifacient Agents, NonsteroidalMethotrexatePregnancy, EctopicTertiary Care CentersAdultCesarean SectionCicatrixFemaleHumansPregnancyPregnancy, AbdominalPregnancy, InterstitialPregnancy, OvarianRetrospective StudiesRisk FactorsTreatment OutcomeAbortifacient Agents, NonsteroidalMethotrexateCesarean Scar PregnancyEctopic PregnancyManual vacuum aspirationMethotrexateNon-TubalSurgery

Identifiers

PMID38252304
OpenAlexW4391107804

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.