Evidence map›Paper›PMID 38252177›Full record

ArticleBotanical studies2024

Antibacterial, antioxidant, and anticancer potential of green fabricated silver nanoparticles made from Viburnum grandiflorum leaf extract.

Hina Talib, Ansar Mehmood, Muhammad Shoaib Amjad, Amna Mustafa, Muhammad Abdul Rauf Khan, Muhammad Raffi, Rizwan Taj Khan, Khawaja Shafique Ahmad, Huma Qureshi

Abstract read
In one paragraph

Article in Botanical studies, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Fabrication of Nano-Silver Composite UsingInternational journal of nanomedicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hina TalibDepartment of Botany, University of Poonch Rawalakot, Rawalakot, Azad Kashmir, 12350, Pakistan.
Ansar MehmoodDepartment of Botany, University of Poonch Rawalakot, Rawalakot, Azad Kashmir, 12350, Pakistan. ansarmehmood@upr.edu.pk.
Muhammad Shoaib AmjadDepartment of Botany, Women University of Azad Jammu and Kashmir Bagh, Bagh, 12500, Pakistan. malikshoaib1165@yahoo.com.
Amna MustafaDepartment of Botany, University of Poonch Rawalakot, Rawalakot, Azad Kashmir, 12350, Pakistan.
Muhammad Abdul Rauf KhanDepartment of Physics, University of Poonch Rawalakot, Rawalakot, Azad Kashmir, 12350, Pakistan.
Muhammad RaffiDepartment of Materials Engineering, National Institute of Lasers and Optronics (NILOP), Lehtrar Road, Nilore, Islamabad, 45650, Pakistan.
Rizwan Taj KhanDepartment of Botany, University of Azad Jammu & Kashmir, Muzaffarabad, Pakistan.
Khawaja Shafique AhmadDepartment of Botany, University of Poonch Rawalakot, Rawalakot, Azad Kashmir, 12350, Pakistan.
Huma QureshiDepartment of Botany, University of Chakwal, Chakwal, 48800, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecently, researchers are focusing on creating new tools to combat the antibiotic resistant bacteria and malignancy issues, which pose significant threats to humanity. Biosynthesized silver nanoparticles (AgNPs) are thought to be a potential solution to these issues. The biosynthesis method, known for its environmentally friendly and cost-effective characteristics, can produce small-sized AgNPs with antimicrobial and anticancer properties. In this study, AgNPs were bio-fabricated from the distilled water and methanolic extracts of Viburnum grandiflorum leaves. Physio-chemical characterization of the bio-fabricated AgNPs was conducted using UV-visible spectroscopy, scanning electron microscopy, energy dispersive X-ray, and X-ray diffraction analysis.

resultsAgNPs produced from the methanol extract were smaller in size (12.28 nm) compared to those from the aqueous extract (17.77 nm). The bioengineered AgNPs exhibited a circular shape with a crystalline nature. These biosynthesized AgNPs demonstrated excellent bactericidal activity against both gram-negative (Pseudomonas aeruginosa) and gram-positive (Staphylococcus aureus) bacteria. Highest antibacterial activity was observed with the methanol extract against P. aeruginosa (14.66 ± 0.74 mm). AgNPs from the methanol extract also displayed the highest antioxidant activity, with an IC

conclusionThe methanol extract of V. grandiflorum leaves demonstrates significant potential for synthesizing AgNPs with effective antibacterial, antioxidant, and anticancer actions, making them applicable in various biomedical applications.

Indexed as

2,2-diphenyl-1-picrylhydrazylAntibiotics resistant bacteriaGreen fabricated Ag nanoparticlesMTT assayPhysiochemical analysisRhabdomyosarcoma cancer cell lines

Identifiers

PMID38252177
PMCPMC10803688

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.