Evidence map›Paper›PMID 38251374›Full record

ArticlePathogens (Basel, Switzerland)2024

Paracrine Signaling Mediated by the Cytosolic Tryparedoxin Peroxidase of

María Laura Chiribao, Florencia Díaz-Viraqué, María Gabriela Libisch, Carlos Batthyány, Narcisa Cunha, Wanderley De Souza, Adriana Parodi-Talice, Carlos Robello

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Placental Barrier Breakdown Induced byInternational journal of molecular sciences · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

María Laura ChiribaoDepartamento de Bioquímica, Facultad de Medicina, Universidad de la República, Montevideo 11000, Uruguay.ORCID 0000-0002-8761-6128
Florencia Díaz-ViraquéLaboratorio de Interacciones Hospedero-Patógeno-UBM, Institut Pasteur Montevideo, Montevideo 11000, Uruguay.ORCID 0000-0003-0181-3671
María Gabriela LibischLaboratorio de Interacciones Hospedero-Patógeno-UBM, Institut Pasteur Montevideo, Montevideo 11000, Uruguay.
Carlos BatthyányLaboratory of Vascular Biology and Drug Development, Institut Pasteur Montevideo, Montevideo 11000, Uruguay.
Narcisa CunhaInstituto de Biofísica Carlos Chagas Filho, Centro Nacional de Biologia Estrutural e Bioimagem (CENABIO), Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.
Wanderley De SouzaInstituto de Biofísica Carlos Chagas Filho, Centro Nacional de Biologia Estrutural e Bioimagem (CENABIO), Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.
Adriana Parodi-TaliceLaboratorio de Interacciones Hospedero-Patógeno-UBM, Institut Pasteur Montevideo, Montevideo 11000, Uruguay.
Carlos RobelloDepartamento de Bioquímica, Facultad de Medicina, Universidad de la República, Montevideo 11000, Uruguay.ORCID 0000-0001-6985-6171
Institut Pasteur de Montevideo · UYUniversidad de la República de Uruguay · UYUniversidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peroxiredoxins are abundant and ubiquitous proteins that participate in different cellular functions, such as oxidant detoxification, protein folding, and intracellular signaling. Under different cellular conditions, peroxiredoxins can be secreted by different parasites, promoting the induction of immune responses in hosts. In this work, we demonstrated that the cytosolic tryparedoxin peroxidase of

Indexed as

Paracrine CommunicationPeroxidasesProtozoan ProteinsTrypanosoma cruziAnimalsChagas DiseaseCytosolEndoplasmic Reticulum StressEpithelial CellsHumansInterleukin-8MacrophagesMiceVirulence FactorsInterleukin-8PeroxidasesProtozoan Proteinstryparedoxin peroxidaseVirulence FactorsChagas diseaseperoxiredoxinsignalingTrypanosoma cruzitryparedoxin peroxidase

Identifiers

PMID38251374
PMCPMC10818299
OpenAlexW4390703853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.