Evidence map›Paper›PMID 38251311›Full record

ArticlePediatric reports2024

Current Overview of CDKL-5 Deficiency Disorder Treatment.

Giovanni Battista Dell'Isola, Katherin Elizabeth Portwood, Kirsten Consing, Antonella Fattorusso, Arnaldo Bartocci, Pietro Ferrara, Giuseppe Di Cara, Alberto Verrotti, Mauro Lodolo

Open access · goldAbstract readEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Giovanni Battista Dell'IsolaDepartment of Pediatrics, University of Perugia, 06129 Perugia, Italy.
Katherin Elizabeth PortwoodShands Children's Hospital, Department of Child Neurology, University of Florida, Gainesville, FL 32608, USA.
Kirsten ConsingShands Children's Hospital, Department of Child Neurology, University of Florida, Gainesville, FL 32608, USA.ORCID 0009-0007-5861-8048
Antonella FattorussoDepartment of Pediatrics, University of Perugia, 06129 Perugia, Italy.
Arnaldo BartocciNeurophysipathology Service, Villa Margherita, 01027 Montefiascone, Italy.
Pietro FerraraUnit of Pediatrics, Campus Bio-Medico University, 00128 Rome, Italy.
Giuseppe Di CaraDepartment of Pediatrics, University of Perugia, 06129 Perugia, Italy.
Alberto VerrottiDepartment of Pediatrics, University of Perugia, 06129 Perugia, Italy.
Mauro LodoloShands Children's Hospital, Department of Child Neurology, University of Florida, Gainesville, FL 32608, USA.
University of Perugia · ITUF Health Shands Hospital · USUniversità Campus Bio-Medico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CDKL5 deficiency disorder (CDD) is a complex of clinical symptoms resulting from the presence of non-functional or absent CDKL5 protein, a serine-threonine kinase involved in neural maturation and synaptogenesis [...].

Identifiers

PMID38251311
PMCPMC10801578
OpenAlexW4390535027

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.