Evidence map›Paper›PMID 38251221›Full record

ArticleTropical medicine and infectious disease2024

Situation Analysis of Early Implementation of Programmatic Management of Tuberculosis Preventive Treatment among Household Contacts of Pulmonary TB Patients in Delhi, India.

Yasir Alvi, Sairu Philip, Tanu Anand, Palanivel Chinnakali, Farzana Islam, Neeta Singla, Pruthu Thekkur, Ashwani Khanna, B K Vashishat

Abstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  5. Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yasir AlviDepartment of Community Medicine, Hamdard Institute of Medical Sciences and Research, New Delhi 110062, India.ORCID 0000-0002-8601-4440
Sairu PhilipDepartment of Community Medicine, Government Medical College, Kottayam 686008, India.ORCID 0000-0003-1531-9519
Tanu AnandScientist E, Indian Council of Medical Research, Department of Health Research, Ministry of Health and Family Welfare, New Delhi 110029, India.
Palanivel ChinnakaliDepartment of Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry 605006, India.ORCID 0000-0001-8320-1016
Farzana IslamDepartment of Community Medicine, Hamdard Institute of Medical Sciences and Research, New Delhi 110062, India.
Neeta SinglaDepartment of Training, National Institute of TB & Respiratory Disease, New Delhi 110030, India.ORCID 0000-0002-1340-3146
Pruthu ThekkurCentre for Operational Research, International Union Against Tuberculosis and Lung Disease (The Union), 75006 Paris, France.ORCID 0000-0001-5257-5074
Ashwani KhannaDelhi State NTEP, New Delhi 110002, India.
B K VashishatState TB Cell, Gulabi Bagh, New Delhi 110007, India.

Funding

Global Fund to Fight AIDS, Tuberculosis and Malaria Project Axshya Plus
6 · The paper itself

Abstract

Tuberculosis Preventive Treatment (TPT) is a powerful tool for preventing the TB infection from developing into active TB disease, and has recently been expanded to all household contacts of TB cases in India. This study employs a mixed-methods approach to conduct a situational analysis of the initial phase of TPT implementation among household contacts of pulmonary TB patients in three districts of Delhi, India. It was completed using a checklist based assessments, care cascade data, and qualitative analysis. Our observations indicated that organizational structure and planning were established, but implementation of TPT was suboptimal with issues in drug availability and procurement, budget, human resources, and training. Awareness and motivation, and shorter regimen, telephonic assessment, and collaboration with NGOs emerged as enablers. Apprehension about taking TPT, erratic drug supply, long duration of treatment, side effects, overburden, large population, INH resistance, data entry issues, and private provider reluctance emerged as barriers. The study revealed potential solutions for optimizing TPT implementation. It is evident that, while progress has been made in TPT implementation, there is room for improvement and refinement across various domains.

Indexed as

care cascadecontact tracingisoniazid preventive therapy (IPT)latent tuberculosis infectionOperational Research (OR)SORT-IT

Identifiers

PMID38251221
PMCPMC10818279

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.