Evidence map›Paper›PMID 38251212›Full record

ArticleTropical medicine and infectious disease2024

Mortality Trend of Severe COVID-19 in Under-Vaccinated Population Admitted to ICU in French Amazonia.

Séverine Matheus, Stéphanie Houcke, Guy Roger Lontsi Ngoulla, Nicolas Higel, Abesetou Ba, Fabrice Cook, Cyrille Gourjault, Flaubert Nkontcho, Magalie Demar, Mathieu Nacher and 5 more

Open access · goldAbstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 2 countries.

Séverine MatheusIntensive Care Unit, Cayenne General Hospital, Cayenne 97300, French Guiana.
Stéphanie HouckeIntensive Care Unit, Cayenne General Hospital, Cayenne 97300, French Guiana.
Guy Roger Lontsi NgoullaIntensive Care Unit, Cayenne General Hospital, Cayenne 97300, French Guiana.
Nicolas HigelIntensive Care Unit, Cayenne General Hospital, Cayenne 97300, French Guiana.
Abesetou BaIntensive Care Unit, Cayenne General Hospital, Cayenne 97300, French Guiana.
Fabrice CookIntensive Care Unit, Cayenne General Hospital, Cayenne 97300, French Guiana.
Cyrille GourjaultIntensive Care Unit, Cayenne General Hospital, Cayenne 97300, French Guiana.ORCID 0000-0002-3952-7657
Flaubert NkontchoPharmacy Department, Cayenne General Hospital, Cayenne 97300, French Guiana.
Magalie DemarPolyvalent Biology Department, Cayenne General Hospital, Cayenne 97300, French Guiana.ORCID 0000-0003-3414-0821
Mathieu NacherClinical Investigation Center Antilles French Guiana (CIC INSERM 1424), Cayenne General Hospital, Cayenne 97300, French Guiana.ORCID 0000-0001-9397-3204
Félix DjossouTropical Biome and Immunopathology CNRS UMR-9017, Inserm U 1019, Université de Guyane, Cayenne 97300, French Guiana.
Didier HommelIntensive Care Unit, Cayenne General Hospital, Cayenne 97300, French Guiana.
Dabor RésiereIntensive Care Unit, Martinique University Hospital, Fort de France 97261, Martinique.ORCID 0000-0002-7273-2521
Jean Marc PujoTropical Biome and Immunopathology CNRS UMR-9017, Inserm U 1019, Université de Guyane, Cayenne 97300, French Guiana.
Hatem KallelIntensive Care Unit, Cayenne General Hospital, Cayenne 97300, French Guiana.
University of French Guiana · GFCentre Hospitalier Universitaire de Martinique · MQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Until December 2021, French Guiana (FG), located in South America, faced four consecutive COVID-19 epidemic waves. This study sought to analyze the mortality trend of severe COVID-19 patients admitted to the referral ICU of FG. (2) Methods: We conducted a prospective, observational, and non-interventional study in ICU at Cayenne Hospital. We included 383 patients older than 18 admitted with SARS-CoV-2-related pneumonia hospitalized from May 2020 to December 2021. The study covers three periods. Period 1 (Waves 1 and 2, original variant), period 2 (Wave 3, Gamma variant), and period 3 (Wave 4, Delta variant). (3) Results: The median age was 63 years (52-70). Frailty was diagnosed in 36 patients over 70 (32.4%). Only 4.8% of patients were vaccinated. The median ICU LOS was 10 days (6-19). Hospital mortality was 37.3%. It was 30.9% in period 1, 36.6% in period 2 (

Indexed as

COVID-19Delta variantFrench GuianaGamma variantmortality

Identifiers

PMID38251212
PMCPMC10820344
OpenAlexW4390615341

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.