Evidence map›Paper›PMID 38251054›Full record

ReviewNeurology international2024

Post-Traumatic Cerebral Infarction: A Narrative Review of Pathophysiology, Diagnosis, and Treatment.

Roy A Poblete, Charlotte Zhong, Anish Patel, Grace Kuo, Philip Y Sun, Jiayu Xiao, Zhaoyang Fan, Nerses Sanossian, Amytis Towfighi, Patrick D Lyden

Open access · goldAbstract readReview
In one paragraph

Review in Neurology international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. The endovascular treatment strategies of cerebrovascular injuries in traumatic brain injury.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2025
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Roy A PobleteKeck School of Medicine, The University of Southern California, Los Angeles, CA 90033, USA.
Charlotte ZhongKeck School of Medicine, The University of Southern California, Los Angeles, CA 90033, USA.
Anish PatelKeck School of Medicine, The University of Southern California, Los Angeles, CA 90033, USA.
Grace KuoKeck School of Medicine, The University of Southern California, Los Angeles, CA 90033, USA.
Philip Y SunDavid Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0003-4428-6031
Jiayu XiaoKeck School of Medicine, The University of Southern California, Los Angeles, CA 90033, USA.ORCID 0000-0001-7478-6534
Zhaoyang FanKeck School of Medicine, The University of Southern California, Los Angeles, CA 90033, USA.ORCID 0000-0002-2693-0260
Nerses SanossianKeck School of Medicine, The University of Southern California, Los Angeles, CA 90033, USA.
Amytis TowfighiKeck School of Medicine, The University of Southern California, Los Angeles, CA 90033, USA.
Patrick D LydenKeck School of Medicine, The University of Southern California, Los Angeles, CA 90033, USA.
University of Southern California · USUniversity of California, Los Angeles · US

Funding

Southern California Clinical and Translational Science InstituteUL1TR001855 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Thomas A Buchanan, Michele D. Kipke · 2016 to 2026
$81.3M
The NIH SPAN Coordinating CenterU24NS113452 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LYDEN, PATRICK D · 2019 to 2021
$2.4M
Longitudinal and quantitative MR plaque imaging for prediction of response to medical management in symptomatic intracranial atherosclerosisR01HL147355 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FAN, ZHAOYANG · 2019 to 2023
$2.1M
NCATS NIH HHS UL1 TR001855NHLBI NIH HHS R01 HL147355NINDS NIH HHS NS113452NINDS NIH HHS U24 NS113452
6 · The paper itself

Abstract

Traumatic brain injury (TBI) is a common diagnosis requiring acute hospitalization. Long-term, TBI is a significant source of health and socioeconomic impact in the United States and globally. The goal of clinicians who manage TBI is to prevent secondary brain injury. In this population, post-traumatic cerebral infarction (PTCI) acutely after TBI is an important but under-recognized complication that is associated with negative functional outcomes. In this comprehensive review, we describe the incidence and pathophysiology of PTCI. We then discuss the diagnostic and treatment approaches for the most common etiologies of isolated PTCI, including brain herniation syndromes, cervical artery dissection, venous thrombosis, and post-traumatic vasospasm. In addition to these mechanisms, hypercoagulability and microcirculatory failure can also exacerbate ischemia. We aim to highlight the importance of this condition and future clinical research needs with the goal of improving patient outcomes after TBI.

Indexed as

cerebral venous thrombosiscervical artery dissectionstroketraumatic brain injuryvasospasm

Identifiers

PMID38251054
PMCPMC10801491
OpenAlexW4390589914

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.