Evidence map›Paper›PMID 38251050›Full record

ReviewNeurology international2023

Phantosmia in Parkinson's Disease: A Systematic Review of the Phenomenology of Olfactory Hallucinations.

Tommaso Ercoli, Caterina Francesca Bagella, Claudia Frau, Elisa Ruiu, Sabrine Othmani, Giansalvo Gusinu, Carla Masala, Leonardo Antonio Sechi, Paolo Solla, Giovanni Defazio

Open access · goldAbstract readReview
In one paragraph

Review in Neurology international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Redefining Non-Motor Symptoms in Parkinson's Disease.Journal of personalized medicine · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Tommaso ErcoliDepartment of Neurology, University of Sassari, Viale S. Pietro 10, 07100 Sassari, Italy.ORCID 0000-0002-3260-1754
Caterina Francesca BagellaDepartment of Neurology, University of Sassari, Viale S. Pietro 10, 07100 Sassari, Italy.
Claudia FrauDepartment of Neurology, University of Sassari, Viale S. Pietro 10, 07100 Sassari, Italy.
Elisa RuiuDepartment of Neurology, University of Sassari, Viale S. Pietro 10, 07100 Sassari, Italy.
Sabrine OthmaniDepartment of Neurology, University of Sassari, Viale S. Pietro 10, 07100 Sassari, Italy.
Giansalvo GusinuDepartment of Biomedical Sciences, Sassari University, 07100 Sassari, Italy.ORCID 0000-0001-5921-2508
Carla MasalaDepartment of Biomedical Sciences, University of Cagliari, SP 8 Cittadella Universitaria, 09042 Monserrato, Italy.ORCID 0000-0001-5272-8421
Leonardo Antonio SechiDepartment of Biomedical Sciences, Sassari University, 07100 Sassari, Italy.ORCID 0000-0003-0566-2049
Paolo SollaDepartment of Neurology, University of Sassari, Viale S. Pietro 10, 07100 Sassari, Italy.ORCID 0000-0002-2982-0665
Giovanni DefazioDepartment of Translational Biomedicine and Neuroscience, University of Bari, 70121 Bari, Italy.
University of Sassari · ITDepartment of Medical Sciences · RUUniversity of Cagliari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Olfactory dysfunction is a prevalent non-motor symptom in Parkinson's disease (PD), affecting approximately 65-90% of subjects. PD patients may also report odor perception in the absence of any external source, often referred to as olfactory hallucinations (OHs) or phantosmia. This study aims to explore the current understanding of OHs in PD and offer a comprehensive overview of their prevalence and characteristics. We conducted a systematic search of the literature published on PubMed from inception to July 2023 regarding OHs in PD, following PRISMA guidelines. From the 2875 studies identified through database searching, 29 studies fulfilled the necessary criteria and underwent data extraction. The frequency of OHs in PD patients varies widely, ranging from 0.5% to 18.2%, with female prevalence ranging from 36% to 75% of the patients. Olfactory experiences may vary widely, ranging from pleasant scents to unpleasant odors. Several studies have indicated the concurrent presence of other types of hallucinations alongside phantosmia, especially visual and auditory hallucinations. OHs in PD are a type of hallucination that has been largely overlooked. To gain a deeper understanding of OHs in PD patients, the next crucial step should involve the development and validation of a dedicated questionnaire.

Indexed as

non-visual hallucinationsolfactory hallucinationsParkinson’s diseasephantosmia

Identifiers

PMID38251050
PMCPMC10801480
OpenAlexW4390103488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.